Is Truxima a chemotherapy drug?
Truxima (rituximab-abbs) is not a chemotherapy drug, rather it is a biologic that is targeted toward specific antigens (proteins). In this case, Truxima targets the CD20 antigen expressed on the surface of pre-B and mature B-lymphocytes. Truxima forms a complex with the CD20 antigen which causes B-cell death (lysis). Most cases of non-Hodgkin’s lymphoma and chronic lymphocytic leukemia arise from B cells. Truxima is usually used together with chemotherapy treatments.
References
- Truxima (rituximab-abbs) Updated Feb 1, 2022 [Product Information] https://www.drugs.com/pro/truxima.html
Read next
What are biosimilar drugs and how do they compare to biologics?
A biosimilar is a biological product that is similar to a reference biologic (usually the originally approved product) and for which there are no clinically meaningful differences in terms of safety, purity, and potency. One example is Amjevita (adalimumab-atto), the first biosimilar approved for Humira (adalimumab) in 2016. Continue reading
Does Truxima make you gain weight?
Weight gain has been reported in 11% of patients being treated with Truxima (rituximab) for non-Hodgkin’s lymphoma (NHL). Be sure to contact your doctor right away if you have a rapid or unexplained weight gain or fluid retention (edema), nausea, vomiting, diarrhea, or lack of energy when using Truxima, as you may need immediate medical care. Continue reading
What is the success rate of Rituxan (rituximab) in patients with blood cancers?
In patients with hematological or blood cancers, including non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL), Rituxan’s success is measured in a number of ways. It is measured by looking at how long patients responded to treatment (median duration of response), how long they live without their disease progressing (progression-free survival) and how many patients respond to treatment (response rate).
Rituxan treatment improves outcomes in certain patients with NHL. Adding Rituxan alongside standard therapies enhances the response patients have to treatment and improves overall outcomes, including increasing the time patients live for without experiencing a progression of their disease.
Rituxan helps to improve overall survival in certain patients with CLL and also helps to increase the time patients live for without experiencing disease progression. Adding Rituxan alongside standard therapy enhances the response patients have to therapy. Continue reading
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Drug information
- Truxima Information for Consumers
- Truxima prescribing info & package insert (for Health Professionals)
- Side Effects of Truxima (detailed)
Related support groups
- Truxima (5 questions, 4 members)
- Chronic Lymphocytic Leukemia (CLL) (26 questions, 57 members)
- Non-Hodgkin's Lymphoma (15 questions, 39 members)