Is prednisolone best taken in the morning and why?

Medically reviewed by Drugs.com. Last updated on Nov 24, 2020.

Official Answer

by Drugs.com

If you are taking Prednisone just once a day, take it in the morning with breakfast. The morning is best as it mimics the timing of your body's own production of cortisone. Taking your dose of prednisone too late in the evening may cause difficulty sleeping.

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