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Is MorphaBond ER a controlled substance?

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 13, 2023.

Official answer


Yes. MorphaBond ER (morphine sulfate) is a schedule II controlled substance.

MorphaBond ER has been discontinued and is no longer available for use.

What is MorphaBond ER?

MorphaBond ER (morphine sulfate) is an extended-release, abuse-deterrent, opioid analgesic for the treatment of pain severe enough to require daily, around-the-clock, long-term opioid treatment.

MorphaBond ER is administered orally every 12 hours. It is not for use as-needed.

What is a Schedule II Controlled Substance?

Drugs placed in Schedule II of the Controlled Substances Act (CSA) have a high potential for abuse and dependence.

Drugs in Schedule II have a currently accepted medical use in the United States or a currently accepted medical use with severe restrictions. Abuse of these drugs may lead to severe psychological or physical dependence.

Examples of Schedule II substances include morphine, cocaine, hydrocodone, oxycodone, fentanyl, and methylphenidate.

What does Abuse-Deterrent mean?

MorphaBond ER is formulated with inactive ingredients that make the tablet more difficult to manipulate physically or chemically. The abuse-deterrent formulation is designed to prevent abuse via oral consumption, intranasal insufflation, injection, and smoking. Misuse of MorphaBond ER can lead to overdose and death.


U.S. Food and Drug Administration. MORPHABOND™ ER Product Label. Available at [Accessed February 22, 2021]

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