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How long does Opdivo stay in your system?

Medically reviewed by Carmen Pope, BPharm. Last updated on May 30, 2022.

Official answer


Opdivo stays in your system for a very long time, up to 3 to 4 months (100 to 125 days). This is based on the half-life of Opdivo, which is 25 days. The half-life is the time it takes for half of a drug to be removed from the body, and experts have agreed it takes 4 to 5 half-lives for a drug to be completely removed from the body. This calculates out to 100 to 125 days for Opdivo. This means that side effects can still occur because of Opdivo a few months after you stop taking the drug.

  • Opdivo (nivolumab) Updated 05/2022. E.R. Squibb & Sons, L.L.C.,the%20treatment%20of%20bladder%20cancer.

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