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How long does minoxidil take to work?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on July 31, 2025.

Official Answer by Drugs.com

When taken for high blood pressure, minoxidil works to lower blood pressure within 30 minutes. The full effect on blood pressure occurs between 2 and 3 hours. The topical version of minoxidil used to treat hair loss takes 8 weeks to work. The maximum effects of minoxidil for hair loss usually occur around 3-4 months of daily use.

How Can I Tell if Minoxidil is Working?

You might not notice the effects of oral minoxidil on your blood pressure. You can measure your blood pressure at home to see the effects of the medication. Your blood pressure reading should become lower within 30 minutes of taking a dose.

For hair loss, the effects of topical minoxidil are much slower. You might not notice more hair growth for many weeks. You will need to use it every day to see results. This is because your hair grows slowly.

How to Tell If Minoxidil Is Working For Hair Loss: Signs Beyond Shedding

Many users focus on the initial shedding phase, but more subtle early indicators of effectiveness include:

If no progress occurs after 6–8 months of daily use (with good adherence), consult a healthcare provider about possible causes such as non-responsiveness or underlying health conditions. Consider documenting hair with monthly photos for tracking subtle changes.

Minoxidil Shedding: Why It Happens and How to Manage

Hair shedding with new minoxidil use can be alarming but is usually temporary. This is caused by "immediate telogen release": minoxidil shifts hairs from the resting (telogen) into a new growth (anagen) phase. Shedding typically begins 2–6 weeks after starting and stabilizes within 6–10 weeks.

Oral Minoxidil for Hair Loss: What to Expect Month-by-Month

Oral minoxidil treatment offers an alternative for patients who may not respond fully to topical formulations. While not FDA approved, some healthcare professionals still prescribe it off-label for certain individuals. Here is what to expect:

Results can vary by dose and individual response. Some people may notice fine vellus ("peach fuzz") hairs earlier; these often thicken over time as treatment continues.

Related questions

Does Minoxidil Lower Blood Pressure?

Yes, minoxidil can lower blood pressure, but how it acts depends on the form used and the dose. Oral minoxidil was originally developed as a treatment for severe, resistant high blood pressure (hypertension). It works by relaxing and widening (dilating) the small arteries, making it easier for blood to flow and reducing blood pressure. Even with low doses, a mild reduction in blood pressure can occur, but most healthy adults notice minimal change.

Topical minoxidil (the type applied to the scalp for hair growth) is absorbed into the bloodstream only in very small amounts. Most people do not experience a significant drop in blood pressure from topical use. Rarely, hypersensitive individuals might notice a slight effect. Individuals with a history of heart or blood pressure conditions, or those taking other medications for hypertension, should consult their doctor before starting minoxidil in any form.

Combining Minoxidil with Other Treatments

New evidence supports combination therapy for superior results, especially in stubborn or advanced cases:

This is not all the information you need to know about minoxidil for safe and effective use and does not take the place of your doctor’s directions. Review the full patient medication guide and discuss this information and any questions you have with your doctor or other health care provider.

References
  1. Liu, C., Liu, X., Shi, T., Wang, Y., Sui, C., Zhang, W., & Wang, B. (2025). Efficacy and safety of oral minoxidil in the treatment of alopecia: a single-arm rate meta-analysis and systematic review. Frontiers in pharmacology, 16, 1556705. https://doi.org/10.3389/fphar.2025.1556705
  2. Minoxidil tablet [package insert]. Updated February 2024. Actavis Pharma, Inc. Accessed July 27, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab30461c-f8c8-409d-9e24-d58ed8a34873
  3. Patel, P., et. al. Updated June 2024. Minoxidil. In: StatPeals [Internet]. Accessed July 27, 2024 at https://www.ncbi.nlm.nih.gov/books/NBK482378/
  4. Ramírez-Marín, H. A., & Tosti, A. (2022). Role of Oral Minoxidil in Patterned Hair Loss. Indian dermatology online journal, 13(6), 729–733. https://doi.org/10.4103/idoj.idoj_246_22

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