Skip to main content

How long does naproxen stay in your system?

Medically reviewed by Drugs.com. Last updated on Oct 17, 2024.

Official Answer by Drugs.com

After taking your last dose of naproxen it should be out of your system within 93.5 hours. Naproxen has an elimination half life of 12 to 17 hours. This is the time it takes for your body to reduce plasma drug levels by half. It takes approximately 5.5 x elimination half-life for a drug to be eliminated from your system.
Therefore naproxen will be in your system for about 93.5 hours (5.5 x 17 hours).

For more information see:

https://www.drugs.com/pro/naprosyn.html

Read next

Naproxen vs ibuprofen: What's the difference?

Ibuprofen is short acting, while naproxen is long acting and more likely to cause an upset stomach. Naproxen also increases the risk of uncontrolled bleeding in people taking blood thinners by 4-fold, and ibuprofen increases the risk 2-fold. Naproxen and ibuprofen are both NSAIDs so they are similar in many ways, but there are important differences. Continue reading

What cold medicine can you take with diabetes?

If you have diabetes and you catch a cold or flu, there are over-the-counter (OTC) medicines that are safe for you to take to help alleviate your symptoms. Check out our suggestions for pain and fever relievers, cough and congestion medications and more.

Remember to look for cold and flu medicines that are less likely to affect your blood sugar (glucose) levels, including sugar-free and alcohol-free options, or worsen any diabetes complications you may have. Continue reading

What is Caridoxen used for?

Caridoxen is a brand name of a combination medicine available in Mexico that contains naproxen (250mg) and carisoprodol (200mg) which may be used to control pain and inflammation and relieve muscle spasms. Caridoxen may be used as a muscle relaxant. Continue reading

See also:

Related medical questions

Drug information

Related support groups