Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- doxorubicin liposomal
- Pyrelle HB (butabarbital / hyoscyamine / phenazopyridine)
Interactions between your drugs
butabarbital DOXOrubicin liposomal
Applies to: Pyrelle HB (butabarbital / hyoscyamine / phenazopyridine), doxorubicin liposomal
Butabarbital may reduce the blood levels of DOXOrubicin liposomal in some patients, which may make the medication less effective in treating your cancer. Using butabarbital with DOXOrubicin liposomal may also increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You should seek immediate medical attention if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
butabarbital food
Applies to: Pyrelle HB (butabarbital / hyoscyamine / phenazopyridine)
Ask your doctor before using butabarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of butabarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with butabarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hyoscyamine food
Applies to: Pyrelle HB (butabarbital / hyoscyamine / phenazopyridine)
Ask your doctor before using hyoscyamine together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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