Drug Interaction Report

Using peanut allergen extract together with doxazosin may not be advisable. Immunotherapy with peanut allergen extract can sometimes cause severe, even potentially life-threatening allergic reactions that require emergency treatment with epinephrine, and medications like doxazosin can interfere with the body's response to epinephrine and significantly reduce its effectiveness. Talk to your doctor if you have any questions or concerns. Stop using peanut allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Consumption of alcoholic beverages or products containing alcohol within 2 hours of taking peanut allergen extract may increase the risk and severity of allergic reactions that can sometimes occur during treatment with peanut allergen extract. Do not use alcohol two hours before, or two hours after the dosing time of peanut allergen extract. Potentially life-threatening or fatal reactions may occur. Talk to your doctor if you have any questions or concerns. You should also take peanut allergen extract with a meal, preferably in the evening, and do not take peanut allergen extract within 2 hours of bedtime. Stop using peanut allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using doxazosin together with ethanol (alcohol). Using doxazosin with ethanol (alcohol) can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake (especially in you are of Asian descent) and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.