Drug Interaction Report
7 potential interactions and/or warnings found for the following 2 drugs:
- cimetidine
- dolutegravir / rilpivirine
Interactions between your drugs
cimetidine rilpivirine
Applies to: cimetidine, dolutegravir / rilpivirine
By reducing the acidity level in the stomach, cimetidine can decrease the absorption and blood levels of rilpivirine and make the medication less effective against HIV. To minimize the risk of interaction, cimetidine should be taken at least 12 hours before or 4 hours after you take rilpivirine. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
cimetidine dolutegravir
Applies to: cimetidine, dolutegravir / rilpivirine
Information for this minor interaction is available on the professional version.
Drug and food interactions
rilpivirine food
Applies to: dolutegravir / rilpivirine
Food significantly increases the absorption of rilpivirine. You should take each dose of rilpivirine with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Grapefruit juice can also increase the absorption of rilpivirine and should preferably be avoided.
dolutegravir food
Applies to: dolutegravir / rilpivirine
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to professional interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Protonix
Protonix (pantoprazole) is used to treat erosive esophagitis and other conditions involving excess ...
Nexium
Nexium is used to treat GERD and other conditions involving excessive stomach acid. Learn about ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Pepcid
Pepcid is used to treat ulcers in the stomach and for conditions where the stomach produces too ...
Prilosec
Prilosec (omeprazole) is used to treat symptoms of GERD and other conditions caused by excess ...
Carafate
Carafate is an anti-ulcer medication used to treat active duodenal ulcers. Learn about side ...
Pepto-Bismol
Pepto-Bismol is antacid used to treat heart burn, indigestion, diarrhea, gas or an upset stomach ...
Prevacid
Prevacid is used to treat and prevent stomach and intestinal ulcers. Learn about side effects ...
Zantac
Zantac is used to treat and prevent ulcers in the stomach and intestines. Includes Zantac side ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.