Drug Interaction Report
7 potential interactions and/or warnings found for the following 2 drugs:
- chloral hydrate
- Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Interactions between your drugs
chloral hydrate propoxyphene
Applies to: chloral hydrate, Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Using propoxyphene together with chloral hydrate may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should take propoxyphene exactly as prescribed by your doctor. Do not take larger doses or use the drug more frequently than prescribed. Misuse of propoxyphene can lead to serious side effects including death, and the risk may be greater if you have a history of emotional disturbances, suicidal thoughts, or alcohol and drug abuse. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin caffeine
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene), Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
Drug and food interactions
propoxyphene food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Do not use alcohol or medications that contain alcohol while you are receiving treatment with propoxyphene. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. Do not use more than the recommended dose of propoxyphene, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
chloral hydrate food
Applies to: chloral hydrate
Alcohol can increase the nervous system side effects of chloral hydrate such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chloral hydrate. Do not use more than the recommended dose of chloral hydrate, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
aspirin food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
aspirin food
Applies to: Propoxyphene Compound 65 (aspirin / caffeine / propoxyphene)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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