Drug Interaction Report

CarBAMazepine may decrease the blood levels and effects of aprocitentan. Monitor your blood pressure closely and speak with your healthcare provider if you have any questions or concerns. In addition, aprocitentan and carBAMazepine may share similar side effects, such as liver problems, so there is also a possibility that the risk of shared side effects might be increased. Seek immediate medical attention if you notice any nausea, vomiting, pain in the upper right part of your stomach, tiredness, lack of appetite, yellowing of your skin or eyes, dark urine, fever, or itching as these could be signs of a serious liver problem that may occur with aprocitentan treatment. Your doctor may already be aware of these possibilities, but has determined that this is the best course of treatment for you and is monitoring you for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking carBAMazepine. This can cause carBAMazepine levels to increase. You should report signs of carBAMazepine side effects such as nausea, visual disturbances, dizziness, or muscle weakness to your doctor. You should avoid or limit the use of alcohol while being treated with carBAMazepine. Alcohol can increase the nervous system side effects of carBAMazepine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.