Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- zavegepant
- Zicam Sinus Relief (oxymetazoline nasal)
Interactions between your drugs
oxymetazoline nasal zavegepant
Applies to: Zicam Sinus Relief (oxymetazoline nasal), zavegepant
ADJUST DOSING INTERVAL: Concomitant use with nasal decongestants may decrease the absorption and pharmacologic effects of intranasal zavegepant. However, pharmacokinetic studies evaluating the effect of concomitant nasal decongestants on intranasal zavegepant are not available.
MANAGEMENT: Concomitant use of nasal decongestants with zavegepant should be avoided. To minimize the risk of interaction, patients who require a nasal decongestant on a day when zavegepant dosing is required should administer the medications at least one hour after administering zavegepant.
References (1)
- (2023) "Product Information. Zavzpret (zavegepant)." Pfizer U.S. Pharmaceuticals Group
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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