Drug Interaction Report

Asciminib may significantly increase the blood levels and effects of avatrombopag. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Taking avatrombopag with food helps ensure consistent absorption of the medication into the blood stream. You should take each dose of avatrombopag with food at the same time everyday.

Food may reduce the absorption of asciminib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should avoid eating for at least 2 hours before and 1 hour after taking asciminib. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.