Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- azilsartan medoxomil
- heparin
Interactions between your drugs
heparin azilsartan
Applies to: heparin, azilsartan medoxomil
MONITOR: The concomitant use of angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) and heparin or low molecular weight heparins may increase the risk of hyperkalemia. ACE inhibitors, ARBs, and some heparins individually have been associated with increased potassium levels or hyperkalemia. Patients with renal impairment, diabetes, old age, and severe or worsening heart failure may be at a greater risk.
MANAGEMENT: Caution is advised if ACE inhibitors or ARBs are used with heparin or low molecular weight heparin. Serum potassium and renal function should be checked regularly.
References (10)
- (2001) "Product Information. Cozaar (losartan)." Merck & Co., Inc
- (2001) "Product Information. Diovan (valsartan)." Novartis Pharmaceuticals
- (2001) "Product Information. Avapro (irbesartan)." Bristol-Myers Squibb
- (2001) "Product Information. Teveten (eprosartan)." SmithKline Beecham
- (2001) "Product Information. Atacand (candesartan)." Astra-Zeneca Pharmaceuticals
- (2001) "Product Information. Micardis (telmisartan)." Boehringer-Ingelheim
- (2002) "Product Information. Benicar (olmesartan)." Sankyo Pharma
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Perazella MA (2000) "Drug-induced hyperkalemia: old culprits and new offenders." Am J Med, 109, p. 307-14
- (2011) "Product Information. Edarbi (azilsartan)." Takeda Pharmaceuticals America
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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