Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- balsalazide
- Wymox (amoxicillin)
Interactions between your drugs
amoxicillin balsalazide
Applies to: Wymox (amoxicillin), balsalazide
GENERALLY AVOID: Balsalazide may be rendered less effective when administered with certain antibiotics. Balsalazide is acted upon in the lower gut by bacterial azoreduction to produce mesalamine, the therapeutically active ingredient. Although no studies have been done, it is theorized that oral antibiotics can interfere with this reduction to mesalamine.
MANAGEMENT: If the patient must receive oral antibiotics, consideration should be given to using another 5-aminosalicylate such as mesalamine.
References (1)
- (2001) "Product Information. Colazal (balsalazide)." Salix Pharmaceuticals
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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