Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Azulfidine (sulfasalazine)
- potassium aminobenzoate
Interactions between your drugs
sulfaSALAzine potassium aminobenzoate
Applies to: Azulfidine (sulfasalazine), potassium aminobenzoate
CONTRAINDICATED: Potassium aminobenzoate may inactivate antibacterial sulfonamides. Sulfonamides are structural analogues and competitive inhibitors of para-aminobenzoic acid, which is required by bacterial folic acid synthesis. Therefore, sufficient concentrations of potassium para-aminobenzoate may antagonize the antibacterial effects of sulfonamides.
MANAGEMENT: The manufacturer considers concomitant use contraindicated.
References (1)
- (2005) "Product Information. Potaba (potassium aminobenzoate)." Glenwood Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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