Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- sodium bicarbonate / sodium citrate
- thallous chloride, tl-201
Interactions between your drugs
sodium bicarbonate thallous chloride Tl-201
Applies to: sodium bicarbonate / sodium citrate, thallous chloride, tl-201
MONITOR: Coadministration of certain drugs may alter the myocardial uptake of thallous chloride Tl-201 and interfere with results of myocardial imaging studies. Drugs that increase or decrease coronary blood flow or potassium uptake may alter the biodistribution of thallous chloride Tl-201. Use of these drugs with thallous chloride TI-201 during imaging studies may result in a decrease in the number and size of perfusion defects, the appearance of false myocardial defects, and a decrease in myocardial localization and an increase in liver localization.
MANAGEMENT: Clinicians should be aware of possible diagnostic interference by these drugs.
References (3)
- Cerner Multum, Inc. "Australian Product Information."
- (2022) "Product Information. Thallous Chloride Tl 201 (thallous chloride Tl-201)." GE Healthcare
- Nuclear Pharmacy Website. University of Arkansas for Medical Sciences. College of Pharmacy (2015) Drug - Radiopharmaceutical Interactions. http://nuclearpharmacy.uams.edu/nicki.html#tl
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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