Drug Interaction Report

Mibefradil may increase the blood levels of tretinoin. You may be more likely to experience side effects, including a rare but potentially serious condition called pseudotumor cerebri that is associated with elevated pressure in the brain. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor immediately if you develop signs and symptoms of pseudotumor cerebri such as headache, nausea, vomiting, visual disturbances, light sensitivity, or ringing in the ears. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.