Drug Interaction Report

Using acitretin and medroxyPROGESTERone is not recommended. Acitretin can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Never use acitretin if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Taking these drugs can interfere with the contraceptive effect of medroxyPROGESTERone. Because use of acitretin is associated with major birth defects, microdosed 'minipill' progestin preparations are not recommended for women of childbearing potential treated with acitretin. The use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Take acitretin with food. Women must avoid all drinks, food, and medicines (including over-the-counter products) that contain alcohol while taking acitretin or for 2 months after stopping treatment. Alcoholic beverages increase the risk for birth defects while taking acitretin. Acitretin can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Never use acitretin if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy. Talk with your doctor about other possible birth control methods while you are taking acitretin. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.