Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- mecamylamine
- sodium bicarbonate / sodium citrate
Interactions between your drugs
sodium bicarbonate mecamylamine
Applies to: sodium bicarbonate / sodium citrate, mecamylamine
MONITOR: Alkalinization of the urine can decrease the renal elimination of mecamylamine. A more pronounced and prolonged antihypertensive action may result.
MANAGEMENT: Blood pressure should be closely monitored. It may be necessary to decrease mecamylamine dosage.
References (1)
- Allanby KD, Trounce JR (1957) "Excretion of mecamylamine after intravenous and oral administration." Br Med J, 2, p. 1219-21
mecamylamine sodium citrate
Applies to: mecamylamine, sodium bicarbonate / sodium citrate
MONITOR: Alkalinization of the urine can decrease the renal elimination of mecamylamine. A more pronounced and prolonged antihypertensive action may result.
MANAGEMENT: Blood pressure should be closely monitored. It may be necessary to decrease mecamylamine dosage.
References (1)
- Allanby KD, Trounce JR (1957) "Excretion of mecamylamine after intravenous and oral administration." Br Med J, 2, p. 1219-21
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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