Drug Interaction Report

Patiromer can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. This may inactivate both patiromer and the mineral it binds to and reduce the effectiveness of both medications. To avoid or minimize the interaction, the dosing times of patiromer and magnesium salicylate should be separated by several hours. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Patiromer may bind to many different oral medications in the gastrointestinal tract and reduce their absorption into the blood stream. The effectiveness of some oral medications may be decreased when taken with patiromer. To minimize the possibility of interaction, it is recommended that you separate the dosing times of patiromer and any oral medication you take by at least three hours. Talk to your doctor if you are unable to do so or if you have other questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using magnesium salicylate together with ethanol (alcohol). Do not drink alcohol while taking magnesium salicylate. Alcohol can increase your risk of stomach bleeding caused by magnesium salicylate. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.