Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- leucovorin
- Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Interactions between your drugs
leucovorin PHENobarbital
Applies to: leucovorin, Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Some anticonvulsant medications may reduce the blood levels of folic acid. In addition, folic acid treatment may reduce the blood levels of certain anticonvulsants. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if your condition changes or you experience loss of seizure control. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
PHENobarbital aminophylline
Applies to: Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital), Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Using PHENobarbital together with aminophylline may decrease the effects of aminophylline. Contact your doctor if your condition changes or if you experience breathing difficulties. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ePHEDrine aminophylline
Applies to: Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital), Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Information for this minor interaction is available on the professional version.
Drug and food interactions
PHENobarbital food
Applies to: Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Ask your doctor before using PHENobarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of PHENobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with PHENobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ePHEDrine food
Applies to: Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Both ePHEDrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aminophylline food
Applies to: Mudrane GG (aminophylline / ephedrine / guaifenesin / phenobarbital)
Both aminophylline and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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