Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Heparin Sodium (heparin)
- telavancin
Interactions between your drugs
heparin telavancin
Applies to: Heparin Sodium (heparin), telavancin
CONTRAINDICATED: Although telavancin does not interfere with coagulation, it may artificially prolong activated partial thromboplastin time (aPTT) test results for up to 18 hours following its administration. Telavancin binds to the artificial phospholipid surfaces added to common anticoagulation tests, thereby interfering with the ability of the coagulation complexes to assemble on the surface of the phospholipids and promote clotting in vitro.
MANAGEMENT: Concomitant use of telavancin and intravenous unfractionated heparin sodium is considered contraindicated. For patients who require aPTT monitoring while being treated with telavancin, a non-phospholipid dependent coagulation test such as a Factor Xa (chromogenic) assay or an alternative anticoagulant not requiring aPTT monitoring may be considered.
References (1)
- (2009) "Product Information. Vibativ (telavancin)." Theravance Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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