Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- heparin
- landiolol
Interactions between your drugs
heparin landiolol
Applies to: heparin, landiolol
Consumer information for this interaction is not currently available.
MONITOR: The concomitant administration of intravenous heparin with landiolol may reduce landiolol plasma levels and blood pressure. The coadministration of intravenous heparin with landiolol in patients undergoing cardiovascular surgery resulted in a 50% decrease in landiolol plasma concentrations, an increased landiolol circulation time, and heparin-induced hypotension. However, changes in heart rate values were not observed with concomitant use.
MANAGEMENT: Coadministration of intravenous heparin and landiolol be done with caution. If coadministration is clinically necessary, increased monitoring is advised. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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