Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- heme iron polypeptide
- Okebo (doxycycline)
Interactions between your drugs
doxycycline heme iron polypeptide
Applies to: Okebo (doxycycline), heme iron polypeptide
Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food/lifestyle interactions
doxycycline food/lifestyle
Applies to: Okebo (doxycycline)
Consumer information for this interaction is not currently available.
GENERALLY AVOID: The oral bioavailability of quinolone and tetracycline antibiotics may be reduced by concurrent administration of preparations containing polyvalent cations such as aluminum, calcium, iron, magnesium, and zinc. Therapeutic failure may result. The proposed mechanism is chelation of quinolone and tetracycline antibiotics by di- and trivalent cations, forming an insoluble complex that is poorly absorbed from the gastrointestinal tract. Reduced gastrointestinal absorption of the cations should also be considered.
MANAGEMENT: Concomitant administration of oral quinolone and tetracycline antibiotics with preparations containing aluminum, calcium, iron, magnesium, and/or zinc salts should generally be avoided. Otherwise, the times of administration should be staggered by as much as possible to minimize the potential for interaction. Quinolones should typically be dosed either 2 to 4 hours before or 4 to 6 hours after polyvalent cation preparations, depending on the quinolone and formulation. Likewise, tetracyclines and polyvalent cation preparations should typically be administered 2 to 4 hours apart. The prescribing information for the antibiotic should be consulted for more specific dosing recommendations.
doxycycline food/lifestyle
Applies to: Okebo (doxycycline)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Venofer
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Injectafer
Injectafer is an injectable iron replacement product that is injected into a vein and may be used ...
Auryxia
Auryxia is used for hyperphosphatemia of renal failure, iron deficiency anemia
Feraheme
Feraheme infusion is used to treat iron deficiency anemia. Learn about side effects, interactions ...
Vitamin B1
Vitamin B1 is used for beriberi, vitamin b1 deficiency, vitamin/mineral supplementation and ...
Thiamine
Thiamine is used for beriberi, vitamin b1 deficiency, vitamin/mineral supplementation and ...
Ferric carboxymaltose
Ferric carboxymaltose is used for iron deficiency anemia
Learn more
Further information
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