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Ferric carboxymaltose

Generic Name: ferric carboxymaltose (FER ik kar BOX ee MAWL tose)
Brand Name: Injectafer

Medically reviewed on April 24, 2018

What is ferric carboxymaltose?

Ferric carboxymaltose is an iron replacement product. You normally get iron from the foods you eat. Iron helps your body produce red blood cells that carry oxygen through your blood to tissues and organs.

Ferric carboxymaltose is used in adults to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body). Ferric carboxymaltose is usually given when iron taken orally (by mouth) is not effective.

Ferric carboxymaltose may also be used for purposes not listed in this medication guide.

Important Information

You should not use ferric carboxymaltose if you have iron overload disorder, or anemia that is not caused by iron deficiency.

Before taking this medicine

You should not use ferric carboxymaltose if you are allergic to it, or if you have:

Tell your doctor if you have ever had:

It is not known whether ferric carboxymaltose will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

How is ferric carboxymaltose given?

Ferric carboxymaltose is given as an infusion into a vein. A healthcare provider will give you this injection.

Ferric carboxymaltose is usually given in two doses, 7 days apart. Your doctor will determine whether you need a repeat course of these two doses.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when ferric carboxymaltose is injected.

You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your ferric carboxymaltose injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include weakness, joint problems, and problems with balance or walking.

What should I avoid after receiving ferric carboxymaltose?

Iron is contained in many vitamin or mineral supplements. Taking certain products together can cause you to get too much iron. Avoid taking any vitamin or mineral supplement your doctor has not recommended.

Ferric carboxymaltose side effects

Get emergency medical help if you have signs of an allergic reaction: hives; feeling light-headed; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • increased blood pressure--severe headache, pounding in your neck or ears, dizziness, nausea;

  • low levels of phosphorus in your blood--confusion, bone pain, muscle weakness; or

  • high levels of iron stored in your body--metallic taste in the mouth, bloody or tarry stools, vomiting blood, severe shortness of breath, chest pain, pale skin, blue lips or fingernails, loss of consciousness, or seizure (convulsions).

Common side effects may include:

  • nausea;

  • dizziness;

  • high blood pressure;

  • flushing (warmth, redness, or tingly feeling); or

  • low phosphorus levels.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Ferric carboxymaltose dosing information

Usual Adult Dose for Iron Deficiency Anemia:

Patients weighing 50 kg or more: Two doses of 750 mg via slow IV push or infusion separated by at least 7 days
Patients weighing less than 50 kg: Two doses of 15 mg/kg via slow IV push or infusion separated by at least 7 days
Maximum dose: Total cumulative dose should not exceed 1500 mg of iron per course

Comments:
-The dosage is expressed in mg of elemental iron.
-Treatment may be repeated if iron deficiency anemia recurs

Use: Treatment of iron deficiency anemia in adults with an intolerance or unsatisfactory response to oral iron and in adults with non-dialysis dependent chronic kidney disease

What other drugs will affect ferric carboxymaltose?

Other drugs may affect ferric carboxymaltose, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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