Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- alfuzosin
- citrulline
Interactions between your drugs
alfuzosin citrulline
Applies to: alfuzosin, citrulline
MONITOR: Coadministration of L-arginine or L-citrulline may potentiate the hypotensive effects of nitrates and vasodilators. Both L-arginine and L-citrulline are amino acid precursors to nitric oxide, which causes vasodilation and increased blood flow.
MANAGEMENT: Due to potentially additive effects in the vasculature, caution is advised during concomitant use of L-arginine or L-citrulline with nitrates and vasodilators. Blood pressure and heart rate should be closely monitored.
References (1)
- Stokes GS, Barin ES, Gilfillan KL, Kaesemeyer WH (2003) "Interactions of L-arginine, isosorbide mononitrate, and angiotensin II inhibitors on arterial pulse wave." Am J Hypertens, 16, p. 719-24
Drug and food interactions
alfuzosin food
Applies to: alfuzosin
ADJUST DOSING INTERVAL: Administration of alfuzosin with food enhances oral bioavailability. According to the manufacturer, extent of absorption is 50% higher when administered under fed conditions compared to fasting conditions.
MANAGEMENT: To ensure maximal oral absorption, alfuzosin should be administered with or immediately after a meal.
References (1)
- (2003) "Product Information. Uroxatral (alfuzosin)." sanofi-aventis
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Flomax
Flomax (tamsulosin) is used to improve urination in men with benign prostatic hyperplasia. Includes ...
Cialis
Cialis (tadalafil) increase increases blood flow to a certain area of the body and is used to treat ...
Taltz
Taltz (ixekizumab) is used to treat plaque psoriasis, psoriatic arthritis, and ankylosing ...
Proscar
Proscar (finasteride) is used to treat benign prostatic hyperplasia (enlarged prostate). Includes ...
Adcirca
Adcirca is used to treat pulmonary arterial hypertension. Learn about side effects, interactions ...
Cardura
Cardura (doxazosin) is used to treat benign prostatic hyperplasia (enlarged prostate) and high ...
Avodart
Avodart (dutasteride) is used to treat benign prostatic hyperplasia (enlarged prostate gland) ...
Hytrin
Hytrin (terazosin) is an alpha-adrenergic blocker used to treat high blood pressure and enlarged ...
Uroxatral
Uroxatral (alfuzosin) is used to treat an enlarged prostate. Includes Uroxatral side effects ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.