Generic Name: lanthanum carbonate (LAN than um CAR bo nayt)
Brand Names: Fosrenol
What is Fosrenol?
Fosrenol (lanthanum) prevents the body from absorbing phosphate, allowing it to be removed from the body.
Fosrenol is used to lower phosphate levels in patients with end stage kidney disease. High levels of phosphate can make it hard for your body to absorb calcium, which can cause serious medical problems.
Fosrenol may also be used for purposes not listed in this medication guide.
You should not use Fosrenol if you have a bowel obstruction or severe constipation.
Before you take Fosrenol, tell your doctor if you have a stomach ulcer, ulcerative colitis, Crohn's disease, diabetes, any type of bowel obstruction, or a history of colon cancer or intestinal surgery.
The chewable tablet should be chewed completely before you swallow it.
Take this medicine with food or immediately after eating.
Tell your doctor about all other medicines you use, especially antibiotics, seizure medication, heart or blood pressure medication, or a blood thinner.
If you also take thyroid replacement medication, take it at least 2 hours before or after taking Fosrenol. Do not take thyroid medication and lanthanum carbonate at the same time.
Avoid taking an antacid within 2 hours before or after you take lanthanum carbonate. Some antacids can make it harder for your body to absorb lanthanum carbonate.
Before taking this medicine
You should not use Fosrenol if you are allergic to lanthanum carbonate, or if you have:
a bowel obstruction or severe constipation.
To make sure Fosrenol is safe for you, tell your doctor if you have:
a stomach ulcer;
any type of bowel obstruction;
slow digestion or severe constipation;
a history of surgery on your stomach or intestines;
ulcerative colitis, Crohn's disease, diverticulitis;
a history of stomach or intestinal cancer;
problems with your teeth.
If you need to have any type of x-ray or CT scan of your stomach area, tell the doctor ahead of time that you are using Fosrenol.
It is not known whether Fosrenol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether lanthanum carbonate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take Fosrenol?
Take Fosrenol exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Take Fosrenol with food or immediately after eating.
The chewable tablet should be chewed completely before you swallow it. Do not swallow whole. Tell your doctor if you have trouble chewing the tablet.
Sprinkle the oral powder into a small amount of applesauce or other soft food (oral powder will not dissolve in liquid). Swallow right away without chewing. Do not save the mixture for later use.
While using Fosrenol, you may need frequent blood tests.
Store at room temperature away from moisture and heat.
Fosrenol dosing information
Usual Adult Dose for Hyperphosphatemia of Renal Failure:
Initial dose: 1500 mg orally daily; take in divided doses with meals
Titrate in increments of 750 mg/day every 2 to 3 weeks until an acceptable serum phosphate level is reached
Maximum dose: 4500 mg/day
Comments: Most patients will require daily doses between 1500 and 3000 mg to reduce plasma phosphate levels to less than 6 mg/dL.
Use: To reduce serum phosphate levels in patients with end stage renal disease.
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Fosrenol?
Fosrenol can make it harder for your body to absorb other medicines you take by mouth.
If you also take thyroid medication, take it at least 2 hours before or 2 hours after you take Fosrenol.
If you take an antibiotic such as ciprofloxacin (Cipro) or levofloxacin (Levaquin), take the antibiotic at least 1 hour before or 4 hours after you take lanthanum carbonate.
Avoid taking an antacid within 2 hours before or 2 hours after you take Fosrenol.
It may be best to avoid taking any other medications by mouth for several hours before or after you take lanthanum carbonate.
Fosrenol side effects
Get emergency medical help if you have signs of an allergic reaction to Fosrenol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe constipation; or
severe stomach cramps.
Common Fosrenol side effects may include:
upset stomach, stomach pain, nausea, vomiting;
itching, rash; or
tooth injury while chewing the tablet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Fosrenol?
Tell your doctor about all your current medicines, especially medicines that can cause constipation, such as:
heart or blood pressure medication (amlodipine, diltiazem, nifedipine, verapamil, and others);
narcotic pain medicine;
a diuretic or "water pill"; or
Other drugs may interact with lanthanum carbonate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about Fosrenol (lanthanum carbonate)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Fosrenol.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Fosrenol only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2016 Cerner Multum, Inc. Version: 4.03. Revision Date: 2016-04-27, 11:16:40 AM.