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Lanthanum carbonate Pregnancy and Breastfeeding Warnings

Lanthanum carbonate is also known as: Fosrenol

Medically reviewed on April 27, 2018

Lanthanum carbonate Pregnancy Warnings

Animal studies have revealed evidence of reproductive fetal toxicity at high doses. There are no controlled data in human pregnancy.

AU TGA pregnancy category B 3: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals have shown evidence of an increased occurrence of fetal damage, the significance of which is considered uncertain in humans.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is not recommended

AU TGA pregnancy category: B 3
US FDA pregnancy category: C

See references

Lanthanum carbonate Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Unknown

Comments: The effects in the nursing infant are unknown.

There is some evidence that lanthanum may be excreted in breast milk. Animal studies evaluating the excretion of lanthanum in milk following oral treatment with lanthanum carbonate have not been done. Offspring of rats receiving oral doses of lanthanum carbonate 2000 mg/kg/day showed post-natal developmental delays.

See references

References for pregnancy information

  1. "Product Information. Fosrenol (lanthanum carbonate)." Shire US Inc, Florence, KY.
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):
  4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

References for breastfeeding information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. "Product Information. Fosrenol (lanthanum carbonate)." Shire US Inc, Florence, KY.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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