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Yohimbine and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with yohimbine.


Yohimbine High Blood Pressure (Hypertension)

Major Potential Hazard, High plausibility

yohimbine - cardiovascular disease

Yohimbine can cause hypertension and tachycardia at recommended dosages. Large doses may cause hypotension and cardiac conduction disturbances. Therapy with yohimbine is generally not recommended in patients with hypertension, angina pectoris, or heart disease.


  1. Limbird LE eds., Gilman AG, Hardman JG (1995) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: McGraw-Hill
  2. (2001) "Product Information. Yocon (yohimbine)." Glenwood Inc
  3. Grossman E, Rosenthal T, Peleg E, Holmes C, Goldstein DS (1993) "Oral yohimbine increases blood pressure and sympathetic nervous outflow in hypertensive patients." J Cardiovasc Pharmacol, 22, p. 22-6
  4. Mansoor GA (2001) "Herbs and alternative therapies in the hypertension clinic." Am J Hypertens, 14(9 Pt 1), p. 971-5
View all 4 references

Yohimbine drug interactions

There are 32 drug interactions with yohimbine.

Yohimbine disease interactions

There are 5 disease interactions with yohimbine which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.