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Tepadina and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Tepadina (thiotepa).

Minor

Nicotine Thiotepa

Minor Drug Interaction

Coadministration of thiotepa may increase plasma concentrations of drugs that are primarily metabolized by CYP450 2B6. Thiotepa has been shown to be a weak inhibitor of CYP450 2B6 in vitro, although drug interactions studies are not available, and the clinical significance is unknown. Product labeling for the specific CYP450 2B6 substrate should be consulted for additional recommendations and monitoring for increased adverse effects when used concomitantly with thiotepa may be warranted.

References (4)
  1. (2023) "Product Information. Thiotepa (thiotepa)." Meitheal Pharmaceuticals Inc.
  2. (2023) "Product Information. Tepadina (thiotepa)." Link Medical Products Pty Ltd T/A Link Pharmaceuticals, 3
  3. (2022) "Product Information. Thiotepa (thiotepa)." MSN Laboratories Europe Ltd
  4. (2021) "Product Information. Tepadina (thiotepa)." Adienne SA

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Tepadina drug interactions

There are 460 drug interactions with Tepadina (thiotepa).

Tepadina disease interactions

There are 4 disease interactions with Tepadina (thiotepa) which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.