Trandate (labetalol) and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with Trandate (labetalol) which include:
labetalol ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Labetalol and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
labetalol ↔ multivitamins with minerals
Moderate Drug Interaction
Using labetalol together with multivitamin with minerals may decrease the effects of labetalol. Separate the administration times of labetalol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Low plausibility
beta-blockers - hyperlipidemia
Beta-adrenergic receptor blocking agents (aka beta-blockers) may alter serum lipid profiles. Increases in serum VLDL and LDL cholesterol and triglycerides, as well as decreases in HDL cholesterol, have been reported with some beta-blockers. Patients with preexisting hyperlipidemia may require closer monitoring during beta-blocker therapy, and adjustments made accordingly in their lipid-lowering regimen.
- Samuel P, Chin B, Schoenfeld BH, et al "Comparison of the effect of pindolol versus propranolol on the lipid profile in patients treated for hypertension." Br J Clin Pharmacol 24 (1987): s63-4
- Gordon NF, Scott CB, Duncan JJ "Effects of atenolol versus enalapril on cardiovascular fitness and serum lipids in physically active hypertensive men." Am J Cardiol 79 (1997): 1065-9
- Lithell H, Andersson PE "Metabolic effects of carvedilol in hypertensive patients." Eur J Clin Pharmacol 52 (1997): 13-7
Trandate (labetalol) drug Interactions
There are 923 drug interactions with Trandate (labetalol)
Trandate (labetalol) disease Interactions
There are 20 disease interactions with Trandate (labetalol) which include:
- Bradyarrhythmia/Av Block
- Cardiogenic Shock/Hypotension
- Liver Disease
- Cerebrovascular Insufficiency
- Hyperthyroidism Pks
- Ischemic Heart Disease
- Myasthenia Gravis
- Prinzmetal's Variant Angina
Drug Interaction Classification
Do not stop taking any medications without consulting your healthcare provider.