Rebetron (interferon alfa-2b / ribavirin) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Rebetron (interferon alfa-2b / ribavirin):
ribavirin ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.
MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.
- "Product Information. Copegus (ribavirin)." Roche Laboratories, Nutley, NJ.
- "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation, Kenilworth, NJ.
Rebetron (interferon alfa-2b / ribavirin) drug Interactions
There are 227 drug interactions with Rebetron (interferon alfa-2b / ribavirin)
Rebetron (interferon alfa-2b / ribavirin) disease Interactions
There are 8 disease interactions with Rebetron (interferon alfa-2b / ribavirin) which include:
- Autoimmune Diseases
- Renal Dysfunction
- Cardiac Disease
- Cns Dysfunction
- Pulmonary Deterioration
- Renal Dysfunction
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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