Cortrosyn and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Cortrosyn (cosyntropin).
Cosyntropin High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
ACTH - fluid retention
Adrenocorticotropic agents may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Therapy with these agents, particularly if intended for longer than brief periods, should be administered cautiously in patients with preexisting fluid retention or conditions that may be aggravated by these effects. Dietary sodium restriction and potassium supplementation may be advisable. The manufacturers consider the use of adrenocorticotropic agents to be contraindicated in patients with congestive heart failure or uncontrolled hypertension.
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Cortrosyn drug interactions
There are 385 drug interactions with Cortrosyn (cosyntropin).
Cortrosyn disease interactions
There are 20 disease interactions with Cortrosyn (cosyntropin) which include:
- (+) tuberculin test
- adrenal insufficiency
- electrolyte imbalance
- fluid retention
- GI perforation
- hyperadrenocorticism
- infections
- ocular herpes simplex
- osteoporosis
- PUD
- scleroderma
- vaccination
- cirrhosis
- depression/psychoses
- diabetes
- elevated IOP
- hypothyroidism
- myasthenia gravis
- myopathy
- thromboembolism
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.