Celecoxib/tramadol and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with celecoxib / tramadol.
Tramadol Food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
References
- Warrington SJ, Ankier SI, Turner P (1986) "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology, 15, p. 31-7
- Gilman AG, eds., Nies AS, Rall TW, Taylor P (1990) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc.
- (2012) "Product Information. Fycompa (perampanel)." Eisai Inc
- (2015) "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc
Celecoxib High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
NSAIDs - hypertension
Nonsteroidal anti-inflammatory drugs (NSAIDs), including topicals, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. NSAIDs should be used with caution in patients with hypertension. Blood pressure should be monitored closely during the initiation of NSAID therapy and throughout the course of therapy.
References
- (2002) "Product Information. Indocin (indomethacin)." Merck & Co., Inc
- (2002) "Product Information. Naprosyn (naproxen)." Syntex Laboratories Inc
- (2001) "Product Information. Voltaren (diclofenac)." Novartis Pharmaceuticals
- (2001) "Product Information. Relafen (nabumetone)." SmithKline Beecham
- (2001) "Product Information. Feldene (piroxicam)." Pfizer U.S. Pharmaceuticals
- (2001) "Product Information. Dolobid (diflunisal)." Merck & Co., Inc
- (2001) "Product Information. Ansaid (flurbiprofen)." Pharmacia and Upjohn
- (2001) "Product Information. Lodine (etodolac)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Daypro (oxaprozin)." Searle
- (2001) "Product Information. Celebrex (celecoxib)." Searle
- (2012) "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc
- (2016) "Product Information. Flector Patch (diclofenac topical)." Actavis U.S. (Alpharma USPD)
Celecoxib/tramadol drug interactions
There are 899 drug interactions with celecoxib / tramadol.
Celecoxib/tramadol disease interactions
There are 22 disease interactions with celecoxib / tramadol which include:
- asthma
- GI toxicity
- rash
- renal toxicities
- thrombosis
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- anemia
- heart failure
- hepatotoxicity
- hyperkalemia
- hypertension
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
More about celecoxib / tramadol
- celecoxib/tramadol consumer information
- Check interactions
- Compare alternatives
- Reviews (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.