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Kyprolis and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Kyprolis (carfilzomib).


High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

carfilzomib - hypertension

The use of carfilzomib has been associated with hypertension, including hypertensive crisis and hypertensive emergency. It is recommended to monitor blood pressure regularly in all patients, especially in hypertensive patients. Care should be taken and if hypertension cannot be adequately controlled, withhold therapy and consider whether to restart therapy based on a benefit/risk assessment.


  1. "Product Information. Kyprolis (carfilzomib)." Onyx Pharmaceuticals Inc (2012):

Kyprolis drug interactions

There are 300 drug interactions with Kyprolis (carfilzomib).

Kyprolis disease interactions

There are 12 disease interactions with Kyprolis (carfilzomib) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.