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DermacinRx Lexitral PharmaPak and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with DermacinRx Lexitral PharmaPak (capsaicin / diclofenac topical).

Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

NSAIDs - hypertension

Nonsteroidal anti-inflammatory drugs (NSAIDs), including topicals, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. NSAIDs should be used with caution in patients with hypertension. Blood pressure should be monitored closely during the initiation of NSAID therapy and throughout the course of therapy.

References

  1. "Product Information. Indocin (indomethacin)." Merck & Co., Inc PROD (2002):
  2. "Product Information. Naprosyn (naproxen)." Syntex Laboratories Inc PROD (2002):
  3. "Product Information. Voltaren (diclofenac)." Novartis Pharmaceuticals PROD (2001):
  4. "Product Information. Relafen (nabumetone)." SmithKline Beecham PROD (2001):
  5. "Product Information. Feldene (piroxicam)." Pfizer U.S. Pharmaceuticals PROD (2001):
  6. "Product Information. Dolobid (diflunisal)." Merck & Co., Inc PROD (2001):
  7. "Product Information. Ansaid (flurbiprofen)." Pharmacia and Upjohn PROD (2001):
  8. "Product Information. Lodine (etodolac)." Wyeth-Ayerst Laboratories PROD (2001):
  9. "Product Information. Daypro (oxaprozin)." Searle PROD (2001):
  10. "Product Information. Celebrex (celecoxib)." Searle PROD (2001):
  11. "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc (2012):
  12. "Product Information. Flector Patch (diclofenac topical)." Actavis U.S. (Alpharma USPD) (2016):
View all 12 references

DermacinRx Lexitral PharmaPak drug interactions

There are 132 drug interactions with DermacinRx Lexitral PharmaPak (capsaicin / diclofenac topical).

DermacinRx Lexitral PharmaPak disease interactions

There are 5 disease interactions with DermacinRx Lexitral PharmaPak (capsaicin / diclofenac topical) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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