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Piqray and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Piqray (alpelisib).

Moderate

Nicotine Alpelisib

Moderate Drug Interaction

Alpelisib may decrease the blood levels and effects of nicotine. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

Alpelisib Food

Moderate Food Interaction

Food significantly enhances the absorption of alpelisib. You should take each dose of alpelisib at the same time each day with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking alpelisib with food. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Piqray drug interactions

There are 334 drug interactions with Piqray (alpelisib).

Piqray disease interactions

There are 6 disease interactions with Piqray (alpelisib) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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