Acetaminophen/pamabrom and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with acetaminophen / pamabrom.
Major food/lifestyle interactions
Major:
Acetaminophen Food/Lifestyle
Major Food Interaction
Generally avoid
Chronic, excessive consumption of alcohol may increase the risk of acetaminophen-induced hepatotoxicity, which has included rare cases of fatal hepatitis and frank hepatic failure requiring liver transplantation. The proposed mechanism is induction of hepatic microsomal enzymes during chronic alcohol use, which may result in accelerated metabolism of acetaminophen and increased production of potentially hepatotoxic metabolites.
Management
In general, chronic alcoholics should avoid regular or excessive use of acetaminophen. Alternative analgesic/antipyretic therapy may be appropriate in patients who consume three or more alcoholic drinks per day.
The information above is from our professional interaction data. Consumer information is not available for this interaction.
Acetaminophen/pamabrom drug interactions
There are 549 drug interactions with acetaminophen / pamabrom.
Acetaminophen/pamabrom disease interactions
There are 4 disease interactions with acetaminophen / pamabrom which include:
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
