Trofinetide Interactions
There are 407 drugs known to interact with trofinetide. Of the total drug interactions, 8 are major, 396 are moderate, and 3 are minor.
Medications known to interact with trofinetide
Note: Showing generic names only.
A
- acalabrutinib
- albendazole
- alfentanil
- alfuzosin
- aliskiren
- almotriptan
- alpelisib
- alprazolam
- ambrisentan
- amiodarone
- amlodipine
- amprenavir
- apixaban
- apremilast
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- astemizole
- atazanavir
- atogepant
- atorvastatin
- atrasentan
- avacopan
- avanafil
- avapritinib
- axitinib
- azelastine nasal
B
- bedaquiline
- belinostat
- belumosudil
- benzgalantamine
- betamethasone
- bexarotene
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- brincidofovir
- bromocriptine
- budesonide
- buprenorphine
- buspirone
- butorphanol
C
- cabozantinib
- cannabidiol
- capivasertib
- capmatinib
- carbamazepine
- cariprazine
- ceritinib
- cerivastatin
- cevimeline
- chlorpromazine
- ciclesonide
- cilostazol
- cinacalcet
- cisapride
- citalopram
- clarithromycin
- clobazam
- clonazepam
- clopidogrel
- clorazepate
- clozapine
- cobicistat
- cobimetinib
- cocaine nasal
- codeine
- colchicine
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- cortisone
- crizotinib
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
D
- dabrafenib
- daclatasvir
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deflazacort
- delavirdine
- dexamethasone
- diazepam
- diclofenac
- dienestrol topical
- dihydroergotamine
- diltiazem
- disopyramide
- docetaxel
- dofetilide
- donepezil
- doravirine
- doxazosin
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- dronabinol
- dronedarone
- droperidol
- drospirenone
- dutasteride
E
- efavirenz
- elacestrant
- eletriptan
- eliglustat
- empagliflozin
- enfortumab vedotin
- entrectinib
- enzalutamide
- eplerenone
- eravacycline
- ergonovine
- ergotamine
- erythromycin
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etonogestrel
- etoposide
- etravirine
- everolimus
- exemestane
- ezetimibe
F
- fedratinib
- felodipine
- fentanyl
- fesoterodine
- fexinidazole
- fexofenadine
- finasteride
- finerenone
- flibanserin
- fludrocortisone
- flurazepam
- fluticasone
- fluvastatin
- fosamprenavir
- fosaprepitant
G
H
I
- ibrexafungerp
- ibrutinib
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- infigratinib
- irinotecan
- isavuconazonium
- isotretinoin
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ixabepilone
- ixazomib
K
L
- lacosamide
- lansoprazole
- lapatinib
- larotrectinib
- lemborexant
- leniolisib
- letermovir
- letrozole
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lidocaine
- linagliptin
- lomitapide
- lonafarnib
- loratadine
- lorlatinib
- lovastatin
- lumateperone
- lurasidone
M
- macitentan
- maraviroc
- maribavir
- mavorixafor
- medroxyprogesterone
- mefloquine
- meperidine
- methadone
- methotrexate
- methylergonovine
- methylprednisolone
- methysergide maleate
- mibefradil
- midazolam
- midostaurin
- mifepristone
- mirabegron
- mirtazapine
- mitapivat
- mobocertinib
- modafinil
- momelotinib
- mometasone
- montelukast
N
- naldemedine
- naloxegol
- nateglinide
- nefazodone
- nelfinavir
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- nisoldipine
- nitisinone
- norethindrone
- norgestrel
O
- olaparib
- oliceridine
- olmesartan
- omeprazole
- ondansetron
- osilodrostat
- osimertinib
- oxybutynin
- oxycodone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- panobinostat
- paricalcitol
- pazopanib
- pemigatinib
- pexidartinib
- pimecrolimus topical
- pimozide
- pioglitazone
- pitavastatin
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- ponesimod
- pralsetinib
- pravastatin
- praziquantel
- prednisolone
- prednisone
- pretomanid
- progesterone
Q
R
- rabeprazole
- ramelteon
- ranolazine
- red yeast rice
- regorafenib
- relugolix
- repaglinide
- repotrectinib
- resmetirom
- retapamulin topical
- revefenacin
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifaximin
- rilpivirine
- rimegepant
- ripretinib
- ritonavir
- rivaroxaban
- roflumilast
- rolapitant
- romidepsin
- ropivacaine
- rosuvastatin
- rucaparib
- ruxolitinib
S
- salmeterol
- saquinavir
- saxagliptin
- selexipag
- selinexor
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- solifenacin
- sonidegib
- sorafenib
- sotorasib
- sparsentan
- sufentanil
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- telaprevir
- telithromycin
- temsirolimus
- teniposide
- terbinafine
- terfenadine
- testosterone
- testosterone topical
- thiotepa
- tiagabine
- ticagrelor
- tinidazole
- tipranavir
- tivozanib
- tofacitinib
- tolterodine
- tolvaptan
- toremifene
- trabectedin
- tramadol
- trazodone
- tretinoin
- triamcinolone
- triazolam
- tucatinib
U
V
- valbenazine
- valdecoxib
- valsartan
- vandetanib
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vilazodone
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vorapaxar
- voriconazole
- voxelotor
W
Z
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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