Topotecan Drug Interactions
Currently displaying a list of 426 drugs known to interact with topotecan.
- 51 major drug interactions
- 359 moderate drug interactions
- 16 minor drug interactions
Medications known to interact with topotecan
Note: Showing generic names only.
A
- abemaciclib
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- adenovirus vaccine
- afamitresgene autoleucel
- aldesleukin
- alefacept
- alemtuzumab
- allopurinol
- alpelisib
- altretamine
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- asciminib
- atezolizumab
- avacopan
- avapritinib
- avelumab
- axicabtagene ciloleucel
- azacitidine
- azathioprine
B
- baricitinib
- bcg
- bcg vaccine
- belantamab mafodotin
- belinostat
- bendamustine
- berotralstat
- bevacizumab
- bexarotene
- bifidobacterium infantis
- bifidobacterium longum
- bleomycin
- blinatumomab
- bortezomib
- bosutinib
- brentuximab
- brewer's yeast
- brexucabtagene autoleucel
- brigatinib
- busulfan
C
- cabazitaxel
- cabozantinib
- caffeine
- canakinumab
- candida albicans extract
- capecitabine
- capmatinib
- carboplatin
- carfilzomib
- carmustine
- cemiplimab
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- cholera vaccine
- cholera vaccine, live
- ciltacabtagene autoleucel
- cinoxacin
- ciprofloxacin
- cisplatin
- cladribine
- clofarabine
- clozapine
- cobimetinib
- coccidioidin skin test
- copanlisib
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclophosphamide
- cytarabine
D
- dacarbazine
- daclatasvir
- dactinomycin
- danicopan
- daratumumab
- daridorexant
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferiprone
- delafloxacin
- dengue vaccine
- denosumab
- deucravacitinib
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- docetaxel
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- durvalumab
- duvelisib
E
- efalizumab
- efbemalenograstim alfa
- eflapegrastim
- elacestrant
- elagolix
- eliglustat
- elotuzumab
- elranatamab
- eltrombopag
- enasidenib
- encorafenib
- enfortumab vedotin
- enoxacin
- entrectinib
- enzalutamide
- epcoritamab
- epirubicin
- erdafitinib
- eribulin
- etanercept
- etoposide
- etrasimod
F
- fam-trastuzumab deruxtecan
- fexinidazole
- fidaxomicin
- filgrastim
- fingolimod
- flibanserin
- floxuridine
- fludarabine
- fluorouracil
- fostamatinib
- fostemsavir
- futibatinib
G
- ganciclovir
- gatifloxacin
- gemcitabine
- gemifloxacin
- gemtuzumab
- gilteritinib
- givinostat
- glasdegib
- glofitamab
- golimumab
- grepafloxacin
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydroxyurea
I
- ibritumomab
- ibrutinib
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- imatinib
- imetelstat
- inavolisib
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon gamma-1b
- iobenguane I 131
- iodine i 131 tositumomab
- ipilimumab
- irinotecan
- irinotecan liposomal
- isatuximab
- isavuconazonium
- istradefylline
- ivosidenib
- ixabepilone
- ixazomib
J
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lasmiditan
- lazertinib
- leflunomide
- lenacapavir
- lenalidomide
- leniolisib
- levacetylleucine
- levamisole
- levofloxacin
- lifileucel
- lisocabtagene maraleucel
- lomefloxacin
- lomitapide
- lomustine
- lonafarnib
- loncastuximab tesirine
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lyme disease vaccine
M
- maribavir
- mavorixafor
- measles virus vaccine
- mechlorethamine
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mercaptopurine
- methotrexate
- midostaurin
- mitapivat
- mitomycin
- mitoxantrone
- mixed respiratory vaccine
- momelotinib
- monomethyl fumarate
- mosunetuzumab
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
N
- nadofaragene firadenovec
- nalidixic acid
- natalizumab
- naxitamab
- nelarabine
- neratinib
- nilotinib
- niraparib
- nivolumab
- norfloxacin
O
- obecabtagene autoleucel
- obinutuzumab
- ocrelizumab
- ofatumumab
- ofloxacin
- olaparib
- omacetaxine
- osimertinib
- oteseconazole
- oxaliplatin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palifermin
- panobinostat
- pazopanib
- pegfilgrastim
- peginterferon alfa-2a
- peginterferon alfa-2b
- pembrolizumab
- pemetrexed
- pemigatinib
- pentostatin
- pertussis, acellular
- pirtobrutinib
- plague vaccine
- plicamycin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- polatuzumab vedotin
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- pomalidomide
- ponatinib
- ponesimod
- pralatrexate
- pralsetinib
- pretomanid
- procarbazine
- promazine
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- resmetirom
- retifanlimab
- revumenib
- ribociclib
- rilonacept
- ripretinib
- ritlecitinib
- rituximab
- roflumilast
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- ruxolitinib
S
- saccharomyces boulardii lyo
- sacituzumab govitecan
- safinamide
- samarium sm 153 lexidronam
- sarecycline
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- selinexor
- selpercatinib
- siponimod
- sipuleucel-T
- sirolimus protein-bound
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- sorafenib
- sotorasib
- sparfloxacin
- sparsentan
- staphage lysate (spl)
- streptococcus salivarius
- streptozocin
- strontium-89 chloride
T
- tafasitamab
- tagraxofusp
- talazoparib
- talimogene laherparepvec
- talquetamab
- tarlatamab
- tazemetostat
- tbo-filgrastim
- teclistamab
- tedizolid
- temozolomide
- teniposide
- tepotinib
- teriflunomide
- tetanus toxoid
- thalidomide
- thioguanine
- thiotepa
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tisagenlecleucel
- tislelizumab
- tisotumab vedotin
- tivozanib
- tofacitinib
- tolvaptan
- toripalimab
- tositumomab
- trabectedin
- trastuzumab
- tremelimumab
- treosulfan
- trichophyton skin test
- trimetrexate
- trovafloxacin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valganciclovir
- varicella virus vaccine
- vemurafenib
- venetoclax
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin e
- voclosporin
Y
Z
- zanidatamab
- zanubrutinib
- zidovudine
- ziv-aflibercept
- zolbetuximab
- zoster vaccine live
- zoster vaccine, recombinant
Topotecan alcohol/food interactions
There is 1 alcohol/food interaction with topotecan.
Topotecan disease interactions
There are 6 disease interactions with topotecan which include:
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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