Propoxyphene Interactions
There are 635 drugs known to interact with propoxyphene, along with 16 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 290 are major, 340 are moderate, and 5 are minor.
- View all 635 medications that may interact with propoxyphene
- View propoxyphene alcohol/food interactions (1)
- View propoxyphene disease interactions (16)
Most frequently checked interactions
View interaction reports for propoxyphene and the medicines listed below.
- Actos (pioglitazone)
- Advair Diskus (fluticasone / salmeterol)
- Ambien (zolpidem)
- Aricept (donepezil)
- Aspirin Low Strength (aspirin)
- Celebrex (celecoxib)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Diovan (valsartan)
- Flomax (tamsulosin)
- Lasix (furosemide)
- Levaquin (levofloxacin)
- Lexapro (escitalopram)
- Lidoderm (lidocaine topical)
- Lipitor (atorvastatin)
- Lortab (acetaminophen / hydrocodone)
- Lyrica (pregabalin)
- Nexium (esomeprazole)
- Norvasc (amlodipine)
- Plavix (clopidogrel)
- Prevacid (lansoprazole)
- Prilosec (omeprazole)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Vicodin (acetaminophen / hydrocodone)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zocor (simvastatin)
Propoxyphene alcohol/food interactions
There is 1 alcohol/food interaction with propoxyphene.
Propoxyphene disease interactions
There are 16 disease interactions with propoxyphene which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
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More about propoxyphene
- propoxyphene consumer information
- Compare alternatives
- Reviews (23)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
