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Darvon-N (propoxyphene) Drug Interactions

A total of 1057 drugs are known to interact with Darvon-N (propoxyphene).

  • 593 major drug interactions
  • 454 moderate drug interactions
  • 10 minor drug interactions

Show all medications in the database that may interact with Darvon-N (propoxyphene).

Check for interactions

Type in a drug name to check for interactions with Darvon-N (propoxyphene).

Most frequently checked interactions

View interaction reports for Darvon-N (propoxyphene) and the medicines listed below.

  • acetaminophen / hydrocodone (Norco, Vicodin, Lortab, Lorcet, Hycet, Anexsia, Vicodin ES, Zydone, Stagesic, Hydrocet, Verdrocet, Lorcet Plus, Lorcet 10/650, Vicodin HP, Maxidone, Xodol, Co-Gesic, Duocet, Duradyne DHC, Hydrogesic, Margesic H, T-Gesic, Lorcet HD, Hy-Phen, Panacet, Vanacet, Dolagesic, Zyfrel, Zolvit, Zamicet, Dolacet, Theracodophen Low 90, Anolor DH5, Liquicet)
  • Ambien (zolpidem)
  • amitriptyline (Elavil, Endep, Vanatrip)
  • Ativan (lorazepam)
  • cephalexin (Keflex, Keftab, Daxbia, Biocef, Zartan, Panixine)
  • ciprofloxacin (Cipro, Cipro XR, Cipro I.V., Cipro Cystitis Pack, Proquin XR)
  • Cymbalta (duloxetine)
  • digoxin (Lanoxin, Digox, Digitek, Lanoxicaps, Cardoxin)
  • Endocet (acetaminophen / oxycodone)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lyrica (pregabalin)
  • Motrin (ibuprofen)
  • nitrofurantoin (Macrobid, Macrodantin, Furadantin, Nitro Macro)
  • Norco (acetaminophen / hydrocodone)
  • phenobarbital (Luminal, Solfoton)
  • propoxyphene (Darvon, Darvon-N, PP-Cap)
  • Prozac (fluoxetine)
  • Soma (carisoprodol)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)

Darvon-N (propoxyphene) alcohol/food interactions

There is 1 alcohol/food interaction with Darvon-N (propoxyphene)

Darvon-N (propoxyphene) disease interactions

There are 16 disease interactions with Darvon-N (propoxyphene) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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