Ponesimod Interactions
There are 674 drugs known to interact with ponesimod, along with 9 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 521 are major, 142 are moderate, and 11 are minor.
- View ponesimod alcohol/food interactions (2)
- View ponesimod disease interactions (9)
Medications known to interact with ponesimod
Note: Showing generic names only.
A
- abarelix
- abatacept
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acebutolol
- adagrasib
- adalimumab
- adenosine
- adenovirus vaccine
- afamitresgene autoleucel
- albuterol
- aldesleukin
- alectinib
- alefacept
- alemtuzumab
- alfuzosin
- allogeneic processed thymus tissue
- altretamine
- amiodarone
- amisulpride
- amitriptyline
- amoxapine
- anagrelide
- anakinra
- anifrolumab
- anthrax vaccine adsorbed
- anti-thymocyte globulin (rabbit)
- apalutamide
- apomorphine
- arformoterol
- aripiprazole
- arsenic trioxide
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atenolol
- atezolizumab
- atomoxetine
- avacopan
- avapritinib
- axicabtagene ciloleucel
- azacitidine
- azathioprine
- azithromycin
B
- baricitinib
- basiliximab
- bcg
- bcg vaccine
- bedaquiline
- belantamab mafodotin
- belatacept
- belimumab
- belinostat
- belzutifan
- bendamustine
- benzgalantamine
- bepridil
- beractant
- betamethasone
- betaxolol
- betaxolol ophthalmic
- bexarotene
- bicalutamide
- bifidobacterium infantis
- bifidobacterium longum
- bimekizumab
- bisacodyl
- bisoprolol
- bitolterol
- black cohosh
- bleomycin
- blinatumomab
- bortezomib
- bosutinib
- brentuximab
- brewer's yeast
- brexucabtagene autoleucel
- brigatinib
- brodalumab
- budesonide
- buprenorphine
- busulfan
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- calfactant
- canakinumab
- candida albicans extract
- cannabidiol
- capecitabine
- carbamazepine
- carboplatin
- carfilzomib
- carmustine
- carteolol
- carteolol ophthalmic
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- cat's claw
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloroquine
- chlorpromazine
- cholera vaccine
- cholera vaccine, live
- cilostazol
- ciltacabtagene autoleucel
- ciprofloxacin
- cisapride
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clofarabine
- clofazimine
- clomipramine
- clonidine
- clozapine
- cobimetinib
- coccidioidin skin test
- copanlisib
- corticorelin
- corticotropin
- cortisone
- cosibelimab
- cosyntropin
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- crovalimab
- cyclophosphamide
- cyclosporine
- cytarabine
D
- dacarbazine
- daclizumab
- dactinomycin
- danicopan
- daratumumab
- daridorexant
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deflazacort
- degarelix
- dengue vaccine
- denileukin diftitox
- denosumab
- desipramine
- deucravacitinib
- deutetrabenazine
- dexamethasone
- dexmedetomidine
- dexrazoxane
- digitoxin
- digoxin
- diltiazem
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- disopyramide
- docetaxel
- dofetilide
- dolasetron
- donepezil
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- dupilumab
- durvalumab
- duvelisib
E
- echinacea
- eculizumab
- edrophonium
- efalizumab
- efavirenz
- efgartigimod alfa
- eflornithine
- elderberry
- elotuzumab
- elranatamab
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- epcoritamab
- epirubicin
- eribulin
- erythromycin
- escitalopram
- eslicarbazepine
- esmolol
- etanercept
- etoposide
- etrasimod
- everolimus
- ezogabine
F
- fam-trastuzumab deruxtecan
- famotidine
- fesoterodine
- fexinidazole
- fingolimod
- flecainide
- floxuridine
- fluconazole
- fludarabine
- fludrocortisone
- fluorouracil
- fluoxetine
- fluphenazine
- flutamide
- formoterol
- foscarnet
- fosphenytoin
- fostemsavir
- fruquintinib
G
- galantamine
- gatifloxacin
- gemcitabine
- gemifloxacin
- gemtuzumab
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glofitamab
- glycerin
- golimumab
- goserelin
- granisetron
- grepafloxacin
- guanfacine
- guselkumab
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- halofantrine
- haloperidol
- halothane
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- histrelin
- human papillomavirus vaccine
- hydrocortisone
- hydroxychloroquine
- hydroxyurea
- hydroxyzine
I
- ibritumomab
- ibrutinib
- ibutilide
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imetelstat
- imipramine
- inavolisib
- indacaterol
- inebilizumab
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon beta-1a
- interferon beta-1b
- interferon gamma-1b
- iobenguane I 131
- iodine i 131 tositumomab
- iptacopan
- irinotecan
- irinotecan liposomal
- isatuximab
- isoetharine
- isoproterenol
- ivabradine
- ivosidenib
- ixabepilone
- ixazomib
- ixekizumab
J
K
L
- labetalol
- lacosamide
- lactitol
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lactulose
- landiolol
- lapatinib
- lasmiditan
- lefamulin
- leflunomide
- lenalidomide
- lenvatinib
- leuprolide
- levalbuterol
- levamisole
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- lifileucel
- linezolid
- lisdexamfetamine
- lisocabtagene maraleucel
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lomustine
- loncastuximab tesirine
- loperamide
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lyme disease vaccine
- lymphocyte immune globulin, anti-thy (equine)
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- mavorixafor
- measles virus vaccine
- mechlorethamine
- mefloquine
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mercaptopurine
- mesoridazine
- metaproterenol
- methadone
- methotrexate
- methotrimeprazine
- methylprednisolone
- metipranolol ophthalmic
- metoprolol
- metronidazole
- midostaurin
- mifepristone
- mineral oil
- mipomersen
- mirikizumab
- mirtazapine
- mitapivat
- mitomycin
- mitoxantrone
- mixed respiratory vaccine
- mobocertinib
- mogamulizumab
- momelotinib
- monomethyl fumarate
- mosunetuzumab
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
- muromonab-cd3
- mycophenolate mofetil
- mycophenolic acid
N
- nadofaragene firadenovec
- nadolol
- naltrexone
- natalizumab
- naxitamab
- nebivolol
- nelarabine
- neostigmine
- nilotinib
- nilutamide
- niraparib
- norfloxacin
- nortriptyline
O
- obecabtagene autoleucel
- obinutuzumab
- ocrelizumab
- ofatumumab
- ofloxacin
- olanzapine
- olaparib
- olaratumab
- oliceridine
- olodaterol
- olutasidenib
- omacetaxine
- omaveloxolone
- ondansetron
- osilodrostat
- osimertinib
- oxaliplatin
- oxytocin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- pasireotide
- pazopanib
- pegaspargase
- pegcetacoplan
- peginterferon alfa-2a
- peginterferon alfa-2b
- peginterferon beta-1a
- pemetrexed
- penbutolol
- pentamidine
- pentostatin
- perflutren
- perphenazine
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenolphthalein
- phenytoin
- pilocarpine
- pimavanserin
- pimozide
- pindolol
- pirbuterol
- pirtobrutinib
- pitolisant
- plague vaccine
- plicamycin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- polatuzumab vedotin
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- pomalidomide
- ponatinib
- posaconazole
- pozelimab
- pralatrexate
- pralsetinib
- prednisolone
- prednisone
- primaquine
- primidone
- probucol
- procainamide
- procarbazine
- prochlorperazine
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyridostigmine
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- ranolazine
- ravulizumab
- relugolix
- remdesivir
- repotrectinib
- revumenib
- ribociclib
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- risankizumab
- risperidone
- ritlecitinib
- ritodrine
- rituximab
- rivastigmine
- roflumilast
- romidepsin
- ropeginterferon alfa-2b
- rotavirus vaccine
- rozanolixizumab
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- ruxolitinib
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- sacituzumab govitecan
- salmeterol
- saquinavir
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- secukinumab
- selinexor
- selpercatinib
- senna
- sertraline
- sevoflurane
- siltuximab
- siponimod
- sipuleucel-T
- sirolimus
- sirolimus protein-bound
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- solifenacin
- sorafenib
- sotalol
- sparfloxacin
- spesolimab
- st. john's wort
- staphage lysate (spl)
- streptococcus salivarius
- streptozocin
- succinylcholine
- sulfamethoxazole
- sunitinib
- sutimlimab
T
- tacrolimus
- tafasitamab
- talazoparib
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tarlatamab
- tazemetostat
- tebentafusp
- teclistamab
- telavancin
- telithromycin
- temozolomide
- temsirolimus
- teniposide
- teplizumab
- terbutaline
- terfenadine
- teriflunomide
- tetanus toxoid
- tetrabenazine
- thalidomide
- thioguanine
- thioridazine
- thiotepa
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tildrakizumab
- timolol
- timolol ophthalmic
- tisagenlecleucel
- tisotumab vedotin
- tizanidine
- tocilizumab
- tofacitinib
- topotecan
- toremifene
- tositumomab
- trabectedin
- tramadol
- trastuzumab
- trazodone
- treosulfan
- triamcinolone
- triamcinolone ophthalmic
- trichophyton skin test
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimetrexate
- trimipramine
- triptorelin
- trofinetide
- tuberculin purified protein derivative
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valbenazine
- vamorolone
- vandetanib
- vardenafil
- varicella virus vaccine
- vasopressin
- vedolizumab
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vilobelimab
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin e
- voclosporin
- vorasidenib
- voriconazole
Y
Z
- zanidatamab
- zanubrutinib
- zidovudine
- zilucoplan
- zinc acetate
- zinc chloride
- zinc gluconate
- zinc sulfate
- ziprasidone
- ziv-aflibercept
- zolbetuximab
- zoster vaccine live
- zoster vaccine, recombinant
Ponesimod alcohol/food interactions
There are 2 alcohol/food interactions with ponesimod.
Ponesimod disease interactions
There are 9 disease interactions with ponesimod which include:
- arrhythmia
- hypertension
- infections
- liver dysfunction
- pulmonary impairment
- vaccination
- encephalopathy
- macular edema
- MS
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More about ponesimod
- ponesimod consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: selective immunosuppressants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
