Paxlovid Drug Interactions
Currently displaying a list of 694 drugs known to interact with Paxlovid (nirmatrelvir / ritonavir).
- 260 major drug interactions
- 392 moderate drug interactions
- 42 minor drug interactions
Medications known to interact with Paxlovid
Note: Showing generic names only.
A
- abametapir topical
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acarbose
- acetohexamide
- acoramidis
- adagrasib
- ado-trastuzumab emtansine
- afatinib
- albendazole
- albiglutide
- aldesleukin
- alfentanil
- alfuzosin
- aliskiren
- almotriptan
- alogliptin
- alosetron
- alpelisib
- alprazolam
- ambrisentan
- aminoglutethimide
- aminophylline
- amiodarone
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amphetamine
- amprenavir
- anisindione
- apalutamide
- apixaban
- aprepitant
- aprocitentan
- aripiprazole
- armodafinil
- artesunate
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atidarsagene autotemcel
- atogepant
- atomoxetine
- atorvastatin
- atovaquone
- atrasentan
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
B
- bedaquiline
- belzutifan
- benzgalantamine
- benznidazole
- bepridil
- berotralstat
- betamethasone
- betaxolol
- betibeglogene autotemcel
- betrixaban
- bexagliflozin
- bexarotene
- binimetinib
- black cohosh
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- brincidofovir
- bromocriptine
- budesonide
- budesonide nasal
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabotegravir
- cabozantinib
- calaspargase pegol
- canagliflozin
- cannabidiol
- cannabis
- capivasertib
- capmatinib
- carbamazepine
- cariprazine
- carvedilol
- cat's claw
- cefamandole
- cefmetazole
- cefonicid
- cefoperazone
- cefotetan
- celecoxib
- cenobamate
- ceritinib
- cerivastatin
- cetirizine
- cevimeline
- chlordiazepoxide
- chloroquine
- chlorpromazine
- chlorpropamide
- ciclesonide
- ciclesonide nasal
- cilostazol
- cinacalcet
- cisapride
- citalopram
- cladribine
- clarithromycin
- clindamycin
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clozapine
- cobicistat
- cobimetinib
- cocaine nasal
- cocaine topical
- codeine
- colchicine
- conivaptan
- conjugated estrogens
- copanlisib
- cortisone
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclatasvir
- daclizumab
- dacomitinib
- danicopan
- dapsone
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deflazacort
- delavirdine
- desipramine
- dexamethasone
- dexamethasone nasal
- dexamethasone ophthalmic
- dexfenfluramine
- dextroamphetamine
- dextromethorphan
- diazepam
- diclofenac
- dicumarol
- didanosine
- digoxin
- dihydroergotamine
- diltiazem
- disopyramide
- disulfiram
- divalproex sodium
- docetaxel
- dofetilide
- dolutegravir
- donepezil
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronabinol
- dronedarone
- droperidol
- drospirenone
- dulaglutide
- duloxetine
- dutasteride
- duvelisib
E
- echinacea
- edoxaban
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- elivaldogene autotemcel
- eluxadoline
- empagliflozin
- encorafenib
- enfortumab vedotin
- enfuvirtide
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- eravacycline
- erdafitinib
- ergonovine
- ergotamine
- erlotinib
- ertugliflozin
- erythromycin
- escitalopram
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estropipate
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
- exenatide
- ezetimibe
F
- febuxostat
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fidanacogene elaparvovec
- fidaxomicin
- finerenone
- flecainide
- flibanserin
- fluconazole
- fludrocortisone
- flunisolide
- flunisolide nasal
- fluorometholone ophthalmic
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- fluticasone
- fluticasone nasal
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
- furazolidone
- futibatinib
G
- gadobenate dimeglumine
- galantamine
- ganaxolone
- garlic
- gefitinib
- gepirone
- gilteritinib
- givosiran
- glasdegib
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- granisetron
- grepafloxacin
- griseofulvin
- guanfacine
H
I
- ibrexafungerp
- ibrutinib
- ibuprofen
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- indomethacin
- infigratinib
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iptacopan
- irbesartan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoniazid
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
K
L
- labetalol
- lacosamide
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lesinurad
- letermovir
- levacetylleucine
- levamlodipine
- levobupivacaine
- levocetirizine
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- liotrix
- liraglutide
- lisdexamfetamine
- lixisenatide
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- loratadine
- lorcaserin
- lorlatinib
- losartan
- loteprednol ophthalmic
- lovastatin
- lovotibeglogene autotemcel
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
M
- macitentan
- maprotiline
- maraviroc
- mavacamten
- mavorixafor
- mebendazole
- medroxyprogesterone
- mefenamic acid
- mefloquine
- melatonin
- meloxicam
- meperidine
- mephobarbital
- mesoridazine
- metformin
- methadone
- methamphetamine
- methdilazine
- methotrexate
- methotrimeprazine
- methylergonovine
- methylprednisolone
- methysergide maleate
- metoclopramide
- metoprolol
- metreleptin
- metronidazole
- metronidazole topical
- mexiletine
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- miglitol
- mipomersen
- mirabegron
- mirtazapine
- mirvetuximab soravtansine
- mitapivat
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- momelotinib
- mometasone
- mometasone nasal
- morphine
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- naproxen
- nateglinide
- nebivolol
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nicardipine
- nifedipine
- nifurtimox
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- norethindrone
- norgestrel
- nortriptyline
O
- olanzapine
- olaparib
- oliceridine
- olutasidenib
- omaveloxolone
- oritavancin
- orlistat
- osilodrostat
- osimertinib
- ospemifene
- oxamniquine
- oxcarbazepine
- oxtriphylline
- oxycodone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- panobinostat
- paricalcitol
- paroxetine
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemigatinib
- penbutolol
- pentobarbital
- perampanel
- perphenazine
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pindolol
- pioglitazone
- piroxicam
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- posaconazole
- pralsetinib
- pramlintide
- pravastatin
- prednisolone
- prednisolone ophthalmic
- prednisone
- pretomanid
- primaquine
- primidone
- prochlorperazine
- proguanil
- promazine
- promethazine
- propafenone
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- prucalopride
Q
R
- raltegravir
- ramelteon
- ranolazine
- red yeast rice
- regorafenib
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- resmetirom
- retapamulin topical
- revefenacin
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- rivaroxaban
- rizatriptan
- roflumilast topical
- rolapitant
- romidepsin
- ropivacaine
- rosiglitazone
- rosuvastatin
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- sacituzumab govitecan
- salmeterol
- saquinavir
- sarecycline
- saxagliptin
- secobarbital
- seladelpar
- selpercatinib
- selumetinib
- semaglutide
- sertraline
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sirolimus topical
- sitagliptin
- sodium zirconium cyclosilicate
- sofpironium topical
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sotagliflozin
- sotorasib
- sparsentan
- st. john's wort
- stiripentol
- sufentanil
- sulfamethoxazole
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- talazoparib
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telotristat
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- theophylline
- thiethylperazine
- thioguanine
- thioridazine
- thiotepa
- thyroid desiccated
- tiagabine
- ticagrelor
- timolol
- timolol ophthalmic
- tinidazole
- tipranavir
- tirzepatide
- tisotumab vedotin
- tofacitinib
- tolazamide
- tolbutamide
- tolterodine
- tolvaptan
- toremifene
- torsemide
- tovorafenib
- trabectedin
- tramadol
- trazodone
- tretinoin
- triamcinolone
- triamcinolone nasal
- triamcinolone ophthalmic
- triazolam
- trifluoperazine
- triflupromazine
- trimeprazine
- trimethoprim
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
U
V
- vadadustat
- valbenazine
- valdecoxib
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vilazodone
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vismodegib
- voclosporin
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Z
Paxlovid alcohol/food interactions
There are 2 alcohol/food interactions with Paxlovid (nirmatrelvir / ritonavir).
Paxlovid disease interactions
There are 7 disease interactions with Paxlovid (nirmatrelvir / ritonavir) which include:
- liver dysfunction
- renal dysfunction
- hemophilia
- hyperglycemia
- hyperlipidemia
- heart block
- hepatotoxicity
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More about Paxlovid (nirmatrelvir / ritonavir)
- Paxlovid consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (533)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: antiviral combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
