Methadone Drug Interactions
Currently displaying 9 drugs known to have a minor interaction with methadone.
- 326 major drug interactions
- 390 moderate drug interactions
- 9 minor drug interactions
Minor interactions with methadone
Note: Showing generic names only.
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Methadone alcohol/food interactions
There are 2 alcohol/food interactions with methadone.
Methadone disease interactions
There are 16 disease interactions with methadone which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.