Opsynvi Interactions
There are 380 drugs known to interact with Opsynvi (macitentan/tadalafil), along with 13 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 62 are major, 222 are moderate, and 96 are minor.
- View all 380 medications that may interact with Opsynvi
- View Opsynvi alcohol/food interactions (1)
- View Opsynvi disease interactions (13)
Most frequently checked interactions
View interaction reports for Opsynvi (macitentan / tadalafil) and the medicines listed below.
- Actemra (tocilizumab)
- Actimmune (interferon gamma-1b)
- Adcetris (brentuximab)
- Adcirca (tadalafil)
- Adempas (riociguat)
- Advair Diskus (fluticasone / salmeterol)
- Adzynma (apadamtase alfa, recombinant)
- Aimovig (erenumab)
- alendronate
- amlodipine
- atorvastatin
- calcium / vitamin d
- Cosentyx (secukinumab)
- Cymbalta (duloxetine)
- Farxiga (dapagliflozin)
- Humira (adalimumab)
- levothyroxine
- lisinopril
- losartan
- Nurtec ODT (rimegepant)
- omeprazole
- Opsumit (macitentan)
- pantoprazole
- potassium chloride
- prednisone
- Skyrizi (risankizumab)
- tadalafil
- Uptravi (selexipag)
- Vitamin D3 (cholecalciferol)
- Wegovy (semaglutide)
Opsynvi alcohol/food interactions
There is 1 alcohol/food interaction with Opsynvi (macitentan / tadalafil).
Opsynvi disease interactions
There are 13 disease interactions with Opsynvi (macitentan / tadalafil) which include:
- hepatotoxicity/liver impairment
- cardiovascular disease
- renal dysfunction
- pulmonary disease
- anemia
- fluid retention
- priapism
- alcoholism
- hearing loss
- liver disease
- retinitis pigmentosa
- seizure disorders
- Tadalafil-visual disorders
Report options
More about Opsynvi (macitentan / tadalafil)
- Opsynvi consumer information
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: agents for pulmonary hypertension
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Adcirca
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Opsumit
Opsumit (macitentan) is used to treat pulmonary arterial hypertension. Includes Opsumit side ...
Revatio
Revatio (sildenafil) is used to treat pulmonary arterial hypertension. Includes Revatio side ...
Adempas
Adempas (riociguat) is used to treat pulmonary hypertension. Includes Adempas side effects ...
Macitentan
Macitentan systemic is used for pulmonary arterial hypertension
Treprostinil
Treprostinil systemic is used for pulmonary arterial hypertension
Ambrisentan
Ambrisentan systemic is used for pulmonary arterial hypertension
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
