Opsynvi Interactions
There are 387 drugs known to interact with Opsynvi (macitentan/tadalafil), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 63 are major, 224 are moderate, and 100 are minor.
- View all 387 medications that may interact with Opsynvi
- View Opsynvi alcohol/food interactions (2)
- View Opsynvi disease interactions (13)
Most frequently checked interactions
View interaction reports for Opsynvi (macitentan / tadalafil) and the medicines listed below.
- amlodipine
- atorvastatin
- calcium / vitamin d
- Cosentyx (secukinumab)
- Cymbalta (duloxetine)
- duloxetine
- famotidine
- Farxiga (dapagliflozin)
- furosemide
- gabapentin
- Humira (adalimumab)
- Jardiance (empagliflozin)
- levothyroxine
- lisinopril
- losartan
- metformin
- mycophenolate mofetil
- Nurtec ODT (rimegepant)
- omeprazole
- Opsumit (macitentan)
- pantoprazole
- potassium chloride
- prednisone
- Skyrizi (risankizumab)
- spironolactone
- tadalafil
- turmeric
- Uptravi (selexipag)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
Opsynvi alcohol/food interactions
There are 2 alcohol/food interactions with Opsynvi (macitentan / tadalafil).
Opsynvi disease interactions
There are 13 disease interactions with Opsynvi (macitentan / tadalafil) which include:
- hepatotoxicity/liver impairment
- cardiovascular disease
- renal dysfunction
- pulmonary disease
- anemia
- fluid retention
- priapism
- alcoholism
- hearing loss
- liver disease
- retinitis pigmentosa
- seizure disorders
- Tadalafil-visual disorders
Report options
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More about Opsynvi (macitentan / tadalafil)
- Opsynvi consumer information
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: agents for pulmonary hypertension
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
