Drug Interactions between clarithromycin and Crestor
This report displays the potential drug interactions for the following 2 drugs:
- clarithromycin
- Crestor (rosuvastatin)
Interactions between your drugs
No interactions were found between clarithromycin and Crestor. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
clarithromycin
A total of 716 drugs are known to interact with clarithromycin.
- Clarithromycin is in the drug class macrolides.
-
Clarithromycin is used to treat the following conditions:
- Bacterial Endocarditis Prevention
- Bronchitis
- Dental Abscess
- Follicular Lymphoma (off-label)
- Helicobacter Pylori Infection
- Legionella Pneumonia
- Middle Ear Infections
- Mycobacterium avium-intracellulare, Prophylaxis
- Mycobacterium avium-intracellulare, Treatment
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Pertussis
- Pertussis Prophylaxis
- Pharyngitis
- Pneumonia
- Sinusitis
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- Strep Throat
- Tonsillitis/Pharyngitis
- Toxoplasmosis
- Upper Respiratory Tract Infection
Crestor
A total of 246 drugs are known to interact with Crestor.
- Crestor is in the drug class statins.
-
Crestor is used to treat the following conditions:
- Atherosclerosis
- High Cholesterol
- High Cholesterol, Familial Heterozygous
- High Cholesterol, Familial Homozygous
- Hyperlipoproteinemia
- Hyperlipoproteinemia Type IIa, Elevated LDL
- Hyperlipoproteinemia Type IIb, Elevated LDL VLDL
- Hyperlipoproteinemia Type III, Elevated beta-VLDL IDL
- Hyperlipoproteinemia Type IV, Elevated VLDL
- Hypertriglyceridemia
- Prevention of Cardiovascular Disease
Drug and food interactions
clarithromycin food
Applies to: clarithromycin
Grapefruit juice may delay the gastrointestinal absorption of clarithromycin but does not appear to affect the overall extent of absorption or inhibit the metabolism of clarithromycin. The mechanism of interaction is unknown but may be related to competition for intestinal CYP450 3A4 and/or absorptive sites. In an open-label, randomized, crossover study consisting of 12 healthy subjects, coadministration with grapefruit juice increased the time to reach peak plasma concentration (Tmax) of both clarithromycin and 14-hydroxyclarithromycin (the active metabolite) by 80% and 104%, respectively, compared to water. Other pharmacokinetic parameters were not significantly altered. This interaction is unlikely to be of clinical significance.
References (1)
- Cheng KL, Nafziger AN, Peloquin CA, Amsden GW (1998) "Effect of grapefruit juice on clarithromycin pharmacokinetics." Antimicrob Agents Chemother, 42, p. 927-9
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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