Drug Interactions between allopurinol and prednisone
This report displays the potential drug interactions for the following 2 drugs:
- allopurinol
- prednisone
Interactions between your drugs
No interactions were found between allopurinol and prednisone. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
allopurinol
A total of 436 drugs are known to interact with allopurinol.
- Allopurinol is in the following drug classes: antigout agents, antihyperuricemic agents.
-
Allopurinol is used to treat the following conditions:
- Calcium Oxalate Calculi with Hyperuricosuria
- Cardiothoracic Surgery (off-label)
- Gout
- High Risk Percutaneous Transluminal Angioplasty (off-label)
- Hyperuricemia Secondary to Chemotherapy
- Leishmaniasis (off-label)
- Mania (off-label)
- Reactive Perforating Collangenosis (off-label)
- Urinary Tract Stones (off-label)
prednisone
A total of 624 drugs are known to interact with prednisone.
- Prednisone is in the drug class glucocorticoids.
-
Prednisone is used to treat the following conditions:
- Acute Lymphocytic Leukemia
- Adrenocortical Insufficiency
- Allergic Reactions
- Allergic Rhinitis
- Allergies
- Amyloidosis
- Ankylosing Spondylitis
- Aspiration Pneumonia
- Asthma
- Atopic Dermatitis
- Autoimmune Hemolytic Anemia
- Berylliosis
- Bullous Pemphigoid
- Bursitis
- Chorioretinitis
- Cluster Headaches
- Cogan's Syndrome
- Congenital Adrenal Hyperplasia
- Conjunctivitis, Allergic
- COPD
- Corneal Ulcer
- Crohn's Disease, Active
- Dermatitis Herpetiformis
- Dermatomyositis
- Diffuse Large B-Cell Lymphoma
- Eczema
- Epicondylitis, Tennis Elbow
- Erythroblastopenia
- Fibromyalgia
- Food Allergies
- Giant Cell Arteritis
- Gouty Arthritis
- Graft Versus Host Disease
- Herpes Zoster
- Herpes Zoster Iridocyclitis
- Hypercalcemia of Malignancy
- Immune Thrombocytopenia
- Immunoglobulin G4-Related Disease
- Immunosuppression
- Inflammatory Bowel Disease
- Inflammatory Conditions
- Interstitial Lung Disease
- Iridocyclitis
- Iritis
- Juvenile Rheumatoid Arthritis
- Keratitis
- Leukemia
- Lichen Planopilaris
- Lichen Planus
- Lichen Sclerosus
- Loeffler's Syndrome
- Lupus
- Lupus Nephritis
- Lymphoma
- Mixed Connective Tissue Disease
- Multiple Sclerosis
- Mycosis Fungoides
- Nephrotic Syndrome
- Neurosarcoidosis
- Optic Neuritis
- Osteoarthritis
- Pemphigoid
- Pemphigus
- Pharyngitis
- Polymyalgia Rheumatica
- Polymyositis/Dermatomyositis
- Psoriasis
- Psoriatic Arthritis
- Ramsay Hunt Syndrome
- Rheumatoid Arthritis
- Sarcoidosis
- Scleroderma
- Seborrheic Dermatitis
- Sinusitis
- Skin Rash
- Synovitis
- Systemic Sclerosis
- Thrombocytopenia
- Toxic Epidermal Necrolysis
- Tuberculosis, Extrapulmonary
- Tuberculous Meningitis
- Ulcerative Colitis, Active
- Uveitis, Posterior
Drug and food interactions
allopurinol food
Applies to: allopurinol
ADJUST DOSING INTERVAL: The tolerability of allopurinol may be improved by giving it after a meal. Additionally, when the dose is greater than 300 mg, dividing the total daily dose into smaller doses administered more often may be appropriate to help minimize gastrointestinal irritation.
MONITOR: Concomitant use of allopurinol with central nervous system (CNS) depressants, including alcohol, may potentiate adverse effects such as somnolence and sedation.
MANAGEMENT: To improve tolerability, some manufacturers suggest administering allopurinol after a meal. Additionally, if the daily dose is greater than 300 mg, administering allopurinol in divided doses may help reduce gastrointestinal intolerance. Patients should also be counseled to avoid or limit consumption of alcohol and to avoid activities requiring mental alertness such as driving or operating hazardous machinery until they know how the medication affects them.
References (4)
- (2024) "Product Information. Allopurinol (Sandoz) (allopurinol)." Sandoz Pty Ltd
- (2021) "Product Information. Zyloric (allopurinol)." Aspen Pharma Trading Ltd
- (2021) "Product Information. Zyloprim (allopurinol)." AA Pharma Inc, 248178
- (2024) "Product Information. Allopurinol (allopurinol)." Actavis U.S. (Purepac Pharmaceutical Company)
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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