Allopurinol/lesinurad Drug Interactions
Currently displaying a list of 604 drugs known to interact with allopurinol / lesinurad.
- 38 major drug interactions
- 547 moderate drug interactions
- 19 minor drug interactions
Medications known to interact with allopurinol/lesinurad
Note: Showing generic names only.
A
- abemaciclib
- abiraterone
- acalabrutinib
- acetylcarbromal
- acrivastine
- adagrasib
- afamitresgene autoleucel
- aldesleukin
- alfentanil
- alpelisib
- alprazolam
- altretamine
- aluminum carbonate
- aluminum hydroxide
- aminophylline
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amoxicillin
- ampicillin
- amprenavir
- anisindione
- apalutamide
- apixaban
- apomorphine
- apremilast
- aprepitant
- aprocitentan
- aripiprazole
- armodafinil
- asciminib
- asenapine
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atogepant
- atropine
- attapulgite
- avacopan
- avanafil
- avapritinib
- axitinib
- azacitidine
- azatadine
- azathioprine
- azelastine nasal
B
- bacampicillin
- baclofen
- bedaquiline
- belinostat
- belladonna
- belumosudil
- benazepril
- bendamustine
- bendroflumethiazide
- benzthiazide
- benztropine
- biperiden
- black cohosh
- bleomycin
- bortezomib
- bosentan
- brentuximab
- brexanolone
- brexpiprazole
- brigatinib
- brivaracetam
- bromocriptine
- brompheniramine
- budesonide
- bumetanide
- buprenorphine
- bupropion
- buspirone
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabergoline
- cabozantinib
- calaspargase pegol
- cannabidiol
- cannabis
- capecitabine
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- carboplatin
- cariprazine
- carisoprodol
- carmustine
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chlorambucil
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- choline salicylate
- ciltacabtagene autoleucel
- cisplatin
- citalopram
- cladribine
- clemastine
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- copanlisib
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cyproheptadine
- cytarabine
- cytarabine liposomal
D
- dabrafenib
- dacarbazine
- daclizumab
- dactinomycin
- dantrolene
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferiprone
- delavirdine
- denileukin diftitox
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- dicumarol
- dicyclomine
- didanosine
- difelikefalin
- diflunisal
- dihydroergotamine
- dihydroxyaluminum sodium carbonate
- dimenhydrinate
- dimethyl fumarate
- diphenhydramine
- diroximel fumarate
- divalproex sodium
- docetaxel
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
- duvelisib
E
- efavirenz
- elacestrant
- elagolix
- enalapril
- enalaprilat
- encorafenib
- enfortumab vedotin
- entacapone
- entecavir
- entrectinib
- enzalutamide
- epirubicin
- ergonovine
- ergotamine
- eribulin
- erlotinib
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- everolimus
- ezogabine
F
- felbamate
- felodipine
- fenfluramine
- fenofibrate
- fentanyl
- fezolinetant
- fidanacogene elaparvovec
- finerenone
- flavoxate
- flibanserin
- floxuridine
- fluconazole
- fludarabine
- fluorouracil
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosamprenavir
- fosinopril
- fosphenytoin
- fostamatinib
- fostemsavir
- furosemide
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- gefitinib
- gemcitabine
- gemfibrozil
- gepirone
- gilteritinib
- glasdegib
- guanabenz
- guanfacine
H
- halazepam
- haloperidol
- heroin
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyurea
- hydroxyzine
- hyoscyamine
I
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imetelstat
- imipramine
- indapamide
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- irinotecan
- irinotecan liposomal
- isocarboxazid
- isoniazid
- isradipine
- ivacaftor
- ivosidenib
- ixabepilone
K
L
- lacosamide
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- lenalidomide
- leniolisib
- letermovir
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- levorphanol
- lidocaine
- lisinopril
- lithium
- lofexidine
- lomitapide
- lomustine
- lonafarnib
- loncastuximab tesirine
- lorazepam
- lorlatinib
- lovastatin
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
M
- macimorelin
- macitentan
- magaldrate
- magnesium salicylate
- maprotiline
- maribavir
- mavacamten
- mechlorethamine
- meclizine
- medroxyprogesterone
- mefloquine
- melatonin
- melphalan
- melphalan flufenamide
- mephenytoin
- mephobarbital
- meprobamate
- mercaptopurine
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methsuximide
- methyclothiazide
- methyldopa
- methylergonovine
- methysergide maleate
- metoclopramide
- metolazone
- metronidazole
- metyrosine
- miconazole
- midazolam
- midostaurin
- mifepristone
- mipomersen
- mirtazapine
- mitapivat
- mitomycin
- mitoxantrone
- mobocertinib
- modafinil
- moexipril
- molindone
- monomethyl fumarate
- morphine
- morphine liposomal
N
- nabilone
- nalbuphine
- naltrexone
- nateglinide
- nefazodone
- nelarabine
- nelfinavir
- nicardipine
- nifedipine
- nimodipine
- nirogacestat
- nisoldipine
- nitisinone
- norethindrone
- norgestrel
- nortriptyline
O
- olanzapine
- olaparib
- oliceridine
- olopatadine nasal
- olutasidenib
- omaveloxolone
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- oxaliplatin
- oxandrolone
- oxazepam
- oxcarbazepine
- oxtriphylline
- oxybutynin
- oxycodone
- oxymorphone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- paliperidone
- palovarotene
- panobinostat
- paraldehyde
- paramethadione
- paroxetine
- pegaspargase
- peginterferon beta-1a
- pegloticase
- pemetrexed
- pemigatinib
- pentazocine
- pentobarbital
- pentostatin
- perampanel
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phencyclidine
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phenytoin
- pimavanserin
- pimozide
- pirtobrutinib
- plicamycin
- polythiazide
- pomalidomide
- ponatinib
- pralatrexate
- pralsetinib
- pramipexole
- praziquantel
- prazosin
- pregabalin
- primidone
- probenecid
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- protriptyline
- pyrazinamide
- pyrilamine
Q
R
- ramelteon
- ramipril
- rasagiline
- red yeast rice
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repotrectinib
- revumenib
- ribociclib
- rifampin
- rifapentine
- rilpivirine
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- romidepsin
- ropinirole
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib topical
S
- sacituzumab govitecan
- safinamide
- salsalate
- saquinavir
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- sildenafil
- silodosin
- simvastatin
- sirolimus
- sirolimus protein-bound
- sodium salicylate
- sodium thiosalicylate
- solifenacin
- sorafenib
- sotorasib
- sparsentan
- st. john's wort
- stiripentol
- streptozocin
- sucralfate
- sufentanil
- sulfadiazine
- sulfamethizole
- sulfamethoxazole
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- tamoxifen
- tapentadol
- tasimelteon
- temazepam
- temozolomide
- temsirolimus
- teniposide
- tepotinib
- terazosin
- teriflunomide
- tetrabenazine
- thalidomide
- theophylline
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiotepa
- thiothixene
- tiagabine
- ticagrelor
- tipranavir
- tizanidine
- tolcapone
- tolterodine
- topiramate
- topotecan
- toremifene
- torsemide
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treosulfan
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trospium
- tucatinib
U
V
- vadadustat
- valbenazine
- valerian
- valoctocogene roxaparvovec
- valproic acid
- vemurafenib
- venlafaxine
- vigabatrin
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vonoprazan
- voriconazole
W
Z
Allopurinol/lesinurad alcohol/food interactions
There is 1 alcohol/food interaction with allopurinol / lesinurad.
Allopurinol/lesinurad disease interactions
There are 8 disease interactions with allopurinol / lesinurad which include:
- secondary hyperuricemia
- severe renal impairment
- bone marrow suppression
- dehydration
- liver disease
- renal dysfunction
- CV disease
- hepatic impairment
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More about allopurinol / lesinurad
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- Check interactions
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- Side effects
- Dosage information
- During pregnancy
- Drug class: antihyperuricemic agents
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
